部份中文磷酸吡哆醛处方资料（仅供参考）
英文名：Pyridoxal Phosphate Hydrate
商品名：Pydoxal
中文名：磷酸吡哆醛注射液
生产商：太阳制药
药品简介 Pydoxal（Pyridoxal Phosphate Hydrate，磷酸吡哆醛）是由维生素B6与磷酸结合形成的，包括吡哆醛、吡哆胺、吡哆醇，在体内以磷酸酯的形式存在。其中磷酸吡哆醛和磷酸吡哆胺可以互相转变，皆为活性型。 ピドキサール注10mg／ピドキサール注30mg
药效分类名称
活性维生素B6制剂
批准日期：1999年7月
商標名
Pydoxal
一般名
ピリドキサールリン酸エステル水和物
（Pyridoxal Phosphate Hydrate）（JAN）
化学名
（4-Formyl-5-hydroxy-6-methylpyridin-3-yl）methyl dihydrogenphosphate monohydrate
構造式
分子式
C8H10NO6P・H2O
分子量
265.16
性状
该产物为淡黄色白色至浅黄色结晶粉末。
该产品微溶于水，几乎不溶于乙醇（99.5）。
该产物可溶于稀盐酸或氢氧化钠TS。
通过将0.1g该产物溶于200mL水中而制备的溶液的pH为3.0至3.5。
由于光照，该产品变为粉红色。
药效药理
磷酸吡rid醛作为辅酶参与许多酶，但代表性的有氨基转移酶（转氨酶），奎奴宁酶，氨基酸脱羧酶和脱水酶，例如基本酶（脱水酶），单胺氧化酶（单胺氧化酶）和组胺降解酶（组胺酶）。
适应症
预防和治疗维生素B6缺乏症（包括通过药物施用，例如异烟肼）
当对维生素B6的需求增加并且饮食中的摄入不足时补充（消耗性疾病，孕妇，哺乳期妇女等）
维生素B6成瘾
（维生素B6反应性贫血等）
在以下疾病中，假定与维生素B6缺乏或代谢异常有关
（1）角性唇炎，唇炎，舌炎，口腔炎
（2）突然/慢性湿疹，脂溢性湿疹，接触性皮炎，特应性皮炎，寻常痤疮
（3）周围神经炎
（4）放射线伤害（宿醉）
在上述适应症（适应症/效果）中，即使对“推测为维生素B6缺乏症或代谢异常的疾病”没有影响，也不应随意使用超过一个月。
用法与用量
成人通常每天皮下注射，肌内注射或静脉内注射1至2次，每次5至60毫克。
剂量可以根据患者的年龄和症状进行调整。
包装
10毫克注射液（1毫升）：10安瓿
10毫克注射液（1 mL）：50安瓿
30毫克注射液（1毫升）：10安瓿
30毫克注射液（1毫升）：50安瓿
制造商和分销商
太阳制药有限公司 注：以上中文处方资料不够完整，使用者以原处方资料为准。
完说明资料附件： https://www.info.pmda.go.jp/go/pack/3134402A1176_2_01/
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PYDOXAL Injection 30mg（Pyridoxal phosphate hydrate）
Brand name:PYDOXAL Injection 30mg
Active ingredient:Pyridoxal phosphate hydrate
Dosage form:injection
Print on wrapping:
Effects of this medicine
This active vitamin B6 preparation works on various metabolism in the body as a coenzyme.
It is usually used to treat anemia and skin/mucosa/nerve inflammation caused by the lack of vitamin B6 as well as tosupply vitamin B6 when its intake from meal is deficient.
Before using this medicine, be sure to tell your doctor and pharmacist
・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinaleffects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
・Your dosing schedule prescribed by your doctor is(( to be written by a healthcare professional))
・In general, inject subcutaneously, intramuscularly or intravenously once or twice a day.
Precautions while taking this medicine
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include hypersensitivity symptoms such as rash. If any of thesesymptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicatedin brackets.If any of these symptoms occur, stop taking this medicine and see your doctor
immediately.
・muscle pain, numbness in the limbs, stiffness, lassitude, red-brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with yourdoctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Injection
Published: 01/2019
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approvaldetails may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response,patients should understand their medication and cooperate with the treatment.
