部份中文奥洛他定资料（仅供参考）
药品英文名
Olopatadine Hydrochloride
药品别名
盐酸奥帕他定、奥罗他定
药物剂型
片剂：10mg。
口腔崩解片：2.5mg，5mg
药理作用
本品能抑制肥大细胞释放过敏介质如组胺、类胰蛋白酶、前列腺素D2，并选择的阻滞H1受体。可抑制Ⅰ型速发性变态反应。对过敏性哮喘症状有抑制作用。
药动学
本品给大鼠和狗口服后tmax分别为0.5和1h。在尿中排泄分别为48%和65%，在粪便中为49%和24%。
适应证
可用于治疗过敏性哮喘和过敏性结膜炎所致的瘙痒。
禁忌证
有药物过敏史的患者不宜使用本品。
注意事项
孕期、哺乳妇女应慎用。
不良反应
常见不良反应是头痛。发生率约7%。其他偶有虚弱、感冒样症状、咽炎、鼻炎、副鼻窦炎和味觉异常等不良反应发生。
用法用量
成人
口服一日两次，每次口服5毫克，睡前服。此外，它会被增加或减少取决于患者的年龄和症状。
孩子
超过7岁的孩子，每次口服5毫克，每日口服2次早上。
包装规格
口腔崩解片：2.5mg
100片（10片×10）
口腔崩解片：5mg
100片（10片×10）
生产厂商：明治药品
Brand name : OLOPATADINE HYDROCHLORIDE OD TABLETS 5 mg "TOWA"
　Active ingredient: Olopatadine hydrochloride
　Dosage form: very light yellow tablet with split line, diameter 8.0 mm, thickness 3.5 mm
　Print on wrapping: オロパタジン塩酸塩OD5mg, 5mg, 口腔内崩壊錠, アレルギー性疾患の薬
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Effects of this medicine
This medicine suppresses production and release of allergic substances (histamine, etc.) in the body. It also resolves and relieves allergic symptoms in skin and nose by inhibiting activities of these allergic substances.
It is usually used in the treatment of allergic rhinitis, hives, and itch associated with skin diseases.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: renal disorder or hepatic disorder.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take 1 tablet (5 mg of the active ingredient) at a time, twice daily, in the morning and before going to bed. The dosage may be adjusted according to the disease, age or symptoms. For children 7 years old or over, take 1 tablet (5 mg) at a time, twice daily, in the morning and before going to bed. Strictly follow the instructions of your doctor or pharmacist.
•This medicine is orally disintegrating tablet. Give this medicine in either of the following ways:
(1) Give this medicine with water or warm water as you do an ordinary tablet.
(2) Place the tablet on patient's tongue, let them crush lightly with the tongue and swallow with saliva. However, never let the patient take the tablet without water when he/she is in a lying position.
•If you miss a morning dose and notice it until noon, take a dose as soon as possible. However, if you notice it late in the day, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•The medicine may cause sleepiness. Avoid driving a car or operating dangerous machinery.
•If you take the medicine for treatment of pollinosis, you need to take the medicine until the pollen season ends.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include sleepiness, malaise, dry mouth and hypersensitivity (rash, oedema, itch, breathing difficulty). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•general malaise, loss of appetite, nausea, yellowing in skin and white of eyes [fulminant hepatitis, hepatic dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00060851
http://www.info.pmda.go.jp/go/pack/4490025F1082_1_04/