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LipaCreon Capsule 150mg(Pancrelipase 胰脂肪酶胶囊)
药店国别  
产地国家 日本 
处 方 药: 是 
所属类别 150毫克/胶囊 120胶囊/盒 
包装规格 150毫克/胶囊 120胶囊/盒 
计价单位: 盒 
生产厂家中文参考译名:
Milan EPD Corporation
生产厂家英文名:
Milan EPD Corporation
该药品相关信息网址1:
http://meds.qlifepro.com/detail/622085401/pancrelipase
该药品相关信息网址2:
该药品相关信息网址3:
原产地英文商品名:
LipaCreon(リパクレオンカプセル)150mg/Capsules 120Capsules/box
原产地英文药品名:
Pancrelipase
中文参考商品译名:
LipaCreon(リパクレオンカプセル)150毫克/胶囊 120胶囊/盒
中文参考药品译名:
胰脂肪酶
曾用名:
简介:

 

部份中文胰脂肪酶处方资料(仅供参考)
英文名:Pancrelipase
商标名:LipaCreon
中文名:胰脂肪酶
剂  型:胶囊、颗粒
生产商:Milan EPD Corporation
リパクレオン顆粒300mg分包/リパクレオンカプセル150mg
药效分类名
酶抑制剂
批准日期:2011年7月
欧文商標名
LipaCreon
一般名
パンクレリパーゼ
Pancrelipase(JAN)
性状
是淡褐色粉末,有点特殊气味。组装的一部分几乎不溶化在水里。
处理上的注意
由于本药剂吸湿后酶活性下降,服用前颗粒不从铝制容器中取出,胶囊则从PTP薄片中取出。
药效药理
消化吸收改善作用
结扎胰腺的胰腺分泌功能衰竭小猪和胰腺不结扎小猪,高脂肪饮食300g(一次喂食脂肪75.4g,蛋白质36.2g和淀粉92.7g;研究了以每天两次作为饲料分析的结果,对给脂肪、蛋白质及淀粉的消化吸收带来本剂的混食效果。根据粪便检计算出的各营养素的消化吸收率如下所示,通过此药,承认脂肪和蛋白质的消化吸收率对容量依赖性增加,不过不承认对淀粉的消化吸收率的影响。(参照从药效药理表迷你猪的粪便检出的各营养素的消化吸收率(%))
药效药理表
根据迷你猪的粪便检出的各营养素的消化吸收率(%)

膵管結紮a) 
本剤c) 
0g 
膵管結紮a) 
本剤
0.53gd)
膵管結紮a) 
本剤
2.12ge)
膵管結紮a) 
本剤
6.35gf)
膵管非結紮b) 
本剤
0g 
脂肪  22.15±5.28  55.67±5.17  66.64±6.83  74.10±5.98  91.38±2.88 
蛋白質  43.72±8.38  57.00±3.73  67.15±4.82  78.90±3.65  87.28±2.42 
デンプン  98.64±0.90  99.69±0.13  99.69±0.09  99.80±0.12  99.72±0.06  
平均值±标准偏差
(a) n=6, b) n=3, c) n=5(除了拒绝进食的一个例子)
d)一次摄食减肥药25,04fip单位,蛋白酶1,581FIP单位以及淀粉酶24,450fip单位
e)一次进食后,轻酶为100,172FIP单位,蛋白酶为624fip单位,氨基酶为97,800FIP单位
f) 1次摄食食内利普30、044FIP单位,蛋白酶18、942FIP单位,氨基酰胺29、938FIP单位
适应症
用法与用量
包装
顆粒300mg分包:
120包,600包
胶囊剂150mg
PTP:120カプセル(12カプセル×10),600カプセル(12カプセル×50)
制造销售
Milan EPD Corporation
注:以上中文处方资料不够完整,使用者以原处方资料为准。
完整说明书附件:http://www.pmda.go.jp/PmdaSearch/iyakuDetail/ResultDataSetPDF/730869_2331007D1029_2_04 

Brand name : LipaCreon Capsule 150mg
 Active ingredient: Pancrelipase
 Dosage form: pale orange / light yellow opaque capsule (entire length: 18 mm) 
 Print on wrapping: (Face) リパクレオンカプセル150mg, 142
(Back) LipaCreon Cap.150mg, リパクレオンカプセル, 150mg, 142
Effects of this medicine
This medicine is a purified pancreatic enzyme from pig. It improves digestion and absorption of lipids and proteins.
It is usually used for pancreatic enzyme replacement in the treatment of exocrine pancreatic insufficiency due to chronic pancreatitis, pancreatectomy, pancreatic cystic fibrosis, etc.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rach, etc.) to any medicines.
If you have a history of hypersensitivity to proteins derived from pig.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take 4 capsules (600 mg of the active ingredient) at a time, three times daily, immediately after meals. The dosage may be adjusted according to the symptoms. Strictly follow the instructions.
•You should take this medicine just after a meal because it may not be sufficiently effective by taking on an empty stomach.
•If you miss a dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include constipation, diarrhea, fever, abdomen enlarged feeling, anal ulcer, gastroenteritis, sty and renal dysfunction. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.  

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