部份中文奥利司他处方资料（仅供参考）
英文名：orlistat
商标名：Alli 60mg Capsules
中文名：奥利司他胶囊
生产商：葛兰素史克
药品介绍
主要功能：阻止多余脂肪吸收并排出多余脂肪 - 排油
用法用量：
口服，随餐服用，1日3次，1次1粒；每日不得超过3粒；建议每天睡觉前补充一粒复合维生素
适用人群：
1. 单纯性肥胖（原发性肥胖）人群
2. 症状性肥胖（继发性肥胖）人群
3. 欲消除宿便并想要美体人群
4. 欲排毒保健人群等
最佳效果使用建议：配合低热量低脂的健康饮食＋适量的体育锻炼，每天睡觉前补充一粒复合维生素。
注意事項：
1. 曾接受器官移植者,请勿使用本产品, 可能会干扰抗排斥药物的作用
2. 对本产品所含任何成份过敏者,请勿使用本产品
3. 体重没有超重的人; 被诊断有食物吸收障碍的人; 或是正在服食免疫抑制剂环孢灵(Cyclosporine)的人, 请勿使用本产品
4. 曾经患有胆囊疾病, 肾结石, 胰腺炎 的人, 使用本产品前请先咨咨专业医生
5. 同时使用其他减重产品, 正在使用薄血药物, 糖尿病或甲状腺药物的人, 用量可能需要调整,请先咨询医生意见
6. 本产品的作用, 在於减少食物中部份脂肪的吸收; 没有被身体吸收的脂肪快速排出体外, 可能造成排便习惯的改变; 您可能会有排油屁, 排便稀软, 排便次数增加, 难以控制等状况发生。
贮存方法：避光，密闭。请放在小孩接触不到的地方。
完整资料附件：https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2d3bd73-f3af-4ea5-a57c-66b0004cfe4f
Pharmacological action Orlistat 120 mg:
Orlistat Specific inhibitor of gastrointestinal lipases. Forms a covalent bond with the active serine site of gastric and pancreatic lipases in the lumen of the stomach and small intestine.
Inactivated the enzyme loses its ability to break down fats, food, coming in the form of triglycerides.
Unsplit TG is not absorbed, and resulting reduction of calorie intake in the body leads to a decrease in body weight.
Increases the concentration of fat in the feces 24-48 h after administration.
Provides effective control of body weight, decrease body fat depot.
Uses Orlistat 120 mg:
Obesity (in the case, unless the diet have led to a weight loss of at least 2.5 kg over 4 weeks).
Contraindications Orlistat 120 mg:
Hypersensitivity, malabsorption syndrome, holestaz.C caution. Pregnancy, lactation.
Side effects Orlistat 120 mg:
Bloating, urgency of defecation, oily stools, increased defecation, fecal incontinence, and allergic reactions.
Dosage and administration:
Inside, 120 mg 3 times daily with each meal or not later than 1 hour after meals (if the food contains no fat, then you can skip the reception.)
Cautions Orlistat 120 mg:
During the period of treatment must be balanced, low-calorie diet containing no more than 30% kalorazh as fat and rich in fruits and vegetables (perhaps a multivitamin supplementation to compensate for the decrease in absorption of fat-soluble vitamins).
Daily consumption of fats, carbohydrates and protein should be distributed in three main reception.
If you take on the background of a diet rich in fat (67g/d), the likelihood of side effects from the gastrointestinal tract is increased. Increasing the dose above the recommended does not lead to increased therapeutic effect.
Treatment should not last more than 2 years. Not intended for use in pediatric practice.
Interaction Orlistat 120 mg:
And increases the bioavailability of lipid-lowering effect of pravastatin, increasing its plasma concentration by 30%. Reduces the absorption of fat soluble vitamins.
Weight loss can improve the metabolism in diabetic patients, resulting need to reduce the dose of oral hypoglycemic drugs.
Clinically significant interactions with digoxin, phenytoin, oral contraceptives, nifedipine, glibenclamide, furosemide, captopril, atenolol, and ethanol were not observed.