部份中文匹可硫酸钠水合物处方资料（仅供参考）
英文名：Sodium Picosulfate Hydrate
商品名：Laxoberon Solution
中文名：盐酸匹可硫酸钠水合物
生产商：帝人制药
药品简介
Laxoberon(Sodium Picosulfate Hydrate,匹可硫酸钠，ラキソベロン)是一种缓泻药，具有独特作用方式的特殊缓泻剂，对大肠黏膜直接作用产生温和的缓泻效果。
ラキソベロン内用液0.75%
药效分类名称
滴剂型泻药/结肠测试预处理泻药
批准日期：2009年9月
商標名
Laxoberon Solution 0.75%
一般名
ピコスルファートナトリウム水和物（Sodium Picosulfate Hydrate）
化学名
Disodium 4,4'-(pyridin-2-ylmethylene)bis(phenyl sulfate)monohydrate
化学構造式
分子式
C18H13NNa2O8S2・H2O
分子量
499.42
性状
它是白色结晶性粉末，无异味。极易溶于水，微溶于甲醇，微溶于乙醇（99.5），几乎不溶于乙醚。 它逐渐被光着色。
药效药理
匹酸钠水合物，胃，小肠中的影响很小，它是通过从结肠菌群酶芳基硫酸酯酶，活性（大鼠）的二酚水解。二酚体示出了泻下作用于肠粘膜以下的效果。
(1) 加强肠道蠕动的作用
(2) 吸湿抑制作用
适应症
便秘症(排便疼痛)
用法用量
1. 各种便秘症
通常情况下，10-15天为成人（0.67〜为1.0mL）口服一次。
孩子每天一次，在下列标准口服给药。此外，想增加或减少取决于患者的年龄和症状。
6月龄以下几点：2滴（0.13mL）
年龄7-12个月：3滴（0.20mL）
年龄1-3岁：6滴（0.40mL）
年龄4-6岁：7滴（0.46mL）
年龄7-15岁：10滴（0.67mL
2.术后排便辅助
通常情况下，10-15天为成人（0.67〜为1.0mL）口服降一次。此外，想增加或减少取决于患者的年龄，症状。
3. 排便促进造影剂（硫酸钡）给药后
通常，6-15下降到成年人（0.40〜为1.0mL）予口服给药。此外，想增加或减少取决于患者的年龄和症状。
4. 消除肠内容物在手术前
正常，14滴为成人（0.93mL）予口服给药。此外，想增加或减少取决于患者的年龄和症状。
5. 消除处理前在大肠检查肠内容物（X射线，内窥镜检查）
通常情况下，20毫升口服给药试验计划时间为成人10至15小时之前。此外，想增加或减少取决于患者的年龄和症状。
包装规格
1）滴型
10毫升×10（定量降落型遮光密闭容器）
10毫升×12（单位剂量容器包装铝在内）
100毫升（棕色玻璃瓶）
在100毫升的包装（褐色玻璃瓶），附加一个校准滴管（液滴数的规模和毫升显示定量滴下类型的容器而言）。
制造商和分销商
帝人制药有限公司
注：以上中文处方资料不够完整，使用者以原处方资料为准。
完整说明资料附件：
https://www.info.pmda.go.jp/go/pack/2359005S1240_1_06/
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Laxoberon Solution 0.75%（Sodium picosulfate hydrate）
Brand name : Laxoberon Solution 0.75% [For constipations, etc.]
　Active ingredient: Sodium picosulfate hydrate
　Dosage form: colorless to light yellow oral solution
　Print on wrapping:
Effects of this medicine
This medicine turns into active form by being degraded by bacteria in the large intestine. It enhances bowl peristalsis and inhibits water absorption to show cathartic action.
It is usually used for constipations, for support of postoperative defecation, for stimulation of defecation after administration of contrast agent (barium sulfate) and for elimination of intestinal contents before surgery.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are suspected of acute abdomen (with abdominal pain).
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>
•For constipations: In general, for adults, take 10 to 15 drops (0.67 to 1.0 mL, 5 to 7.5 mg of the active ingredient) at a time, once a day. For children aged 6 months or younger, take 2 drops (0.13 mL); 7 to 12 months, 3 drops (0.20 mL); 1 to 3 years, 6 drops (0.40 mL); 4 to 6 years, 7 drops (0.46 mL); 7 to 15 years, 10 drops (0.67 mL) at a time, once a day.
For support of postoperative defecation: In general, for adults, take 10 to 15 drops (0.67 to 1.0 mL, 5 to 7.5 mg of the active ingredient) at a time, once a day.
For stimulation of defecation after administration of contrast agent (barium sulfate): In general, for adults, take 6 to 15 drops (0.40 to 1.0 mL, 3 to 7.5 mg of the active ingredient).
For elimination of intestinal contents before surgery: In general, for adults, take 14 drops (0.93 mL, 7.0 mg of the active ingredient).
The dosage may be adjusted according to your age and symptoms in any case. Strictly follow the instructions.
•Drop appropriate amount of solution into a glass of water and drink it. If you have no defecation or become diarrhetic with instructed dosage, consult with your doctor or pharmacist.
•Do not apply this medicine to your eyes. If the medicine accidentally gets into the eye, wash the eye with running water well immediately. If you notice any abnormality, visit your doctor or ophthalmologist.
•If you miss a dose, for constipations, skip the missed dose and continue your regular dosing schedule from the next day. For support of postoperative defecation and for stimulation of defecation after administration of contrast agent, follow the instructions of your doctor. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include abdominal pain, borborygmus, nausea/vomiting, hives or rash. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.