部份中文地贝卡星硫酸盐处方资料（仅供参考）
英文名：Dibekacin Sulfate
商品名：PANIMYCIN
中文名：地贝卡星硫酸盐
生产商：明治制果制药
注射用パニマイシン100mg
药用类别名称
氨基糖苷类抗生素制剂
批准日期：2007年6月
欧文商標名
PANIMYCIN 100mg FOR INJECTION
性　状
ジベカシン硫酸塩は白色〜黄白色の粉末である。
本品は水に極めて溶けやすく、エタノール（99.5）にほとんど溶けない。
一般名
ジベカシン硫酸塩　Dibekacin Sulfate
略　号
DKB
化学名
3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine sulfate
分子式
C18H37N5O8・xH2SO4
分子量
451.52（ただし遊離塩基）
構造式
分配係数
（log10　1-オクタノール層/水層、20±5℃）
（下表参照）

药效药理
1. 体外抗菌活性
下表显示了双曲卡星细菌的最低抑菌浓度 (MIC)。
2. 作用机制
通过抑制细菌的蛋白质合成, 显示出抗菌活性, 其作用是杀菌作用。

(日本化疗社会用最小抑菌浓度(MIC)测量方法)
适应症
＜适应细菌物种 ＞
对地贝金敏感的金黄色葡萄球菌、大肠杆菌、肺炎芽孢杆菌、蛋白质、Molganella Molnney、普罗维登西亚 Rettgelli、铜绿假单胞菌
＜适应症＞
继发感染, 如败血症、深皮感染、慢性化脓性疾病、创伤烧伤和外科伤口、扁桃体炎、急性支气管炎、肺炎、慢性呼吸道病变继发感染、膀胱炎、肾肾炎、腹膜炎症、中耳炎
用法与用量
[在肌肉注意的情况下]
通常, 成人作为双曲卡星, 分为每日剂量100毫克(滴度)的1至2倍, 作为儿童的双氯黄, 1天量1~2mg(滴度)/克分为1-2次, 每次肌肉注射。
[滴注]
通常, 作为成人双人卡星, 分为每日两次剂量100毫克(滴度), 稀释为100至300毫升, 静脉输液超过30分钟至1小时。
在任何情况下年龄, 它是适当的增加或减少的症状。
临床结果
继发感染(支气管炎)、肺炎、肾肾炎肾炎、膀胱炎、腹膜炎、急性支气管炎和深部皮肤感染的慢性呼吸道病变(煮沸、蜂窝炎)、扁桃体炎、结果显示, 766例患者的肌肉笔记抗创伤、烧伤、术后感染(术后感染) 的有效率为72%~100%, 静脉输液的有效率为 56% ~ 100%。
包装规格
注射溶液
1瓶100毫克 (滴度), 含10瓶
制造厂商
明治制果制药
注：以上中文不够完整，使用者以原处方资料为准。
完整资料附件：http://www.info.pmda.go.jp/go/pack/6134400D2033_1_02/
Brand name : PANIMYCIN 100mg FOR INJECTION
　Active ingredient: Dibekacin sulfate
　Dosage form: injection
　Print on wrapping:
Effects of this medicine
This medicine is an aminoglycoside antibiotic which inhibits bacterial protein synthesis to exert an antibacterial effect.
It is usually used to treat sepsis, deep skin infection, chronic pyoderma, secondary infection in injury/burn/surgical wound, tonsillitis, acute bronchitis, pneumonia, secondary infection in chronic respiratory lesion, cystitis, pyelonephritis, peritonitis and otitis media.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you or your family has hearing loss due to aminoglycoside antibiotics or hearing loss due to any other cause.
If you have: renal/liver disorder or myasthenia gravis; you can hardly take food by mouth or are in a parenteral nutrition state; you are in a poor general condition.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products.(Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule(How to take this medicine)
•Your dosing schedule prescribed by your doctor is<<to be written by a healthcare professional>>
•In general, this medicine is administered by intramuscular injection in 1 or 2 divided doses a day or by intravenous infusion in 2 divided doses over a period of 30 minutes to 1 hour.
•The treatment period with this medicine is determined based on your symptoms.
•You should rest in bed from the start to the end of drip infusion.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include pain, renal dysfunction, rash, diarrhea, erythema, edematous erythema, itching and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•feeling unwell, oral cavity discomfort, wheezing[shock]
•decreased urine output, edema, headache[serious renal disorder such as acute renal failure]
•dizziness, tinnitus, hearing loss[VIIIth cranial nerve disorder]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•If you become unwell during an injection, you should tell your doctor immediately.
Meiji Seika Pharma Co., Ltd.Injection
Published: 3/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.