部份中文甲硝唑处方资料（仅供参考）
英文名：METRONIDAZOLE
商品名：ROSADAN 0.75% GEL
中文名：甲硝唑凝胶
生产商：MEDIMETRIKS PHARMA
药品简介
临床药理学
对10名酒渣鼻患者的面部局部给药1克（甲硝唑）凝胶（7.5毫克甲硝唑）的生物利用度研究显示，一名患者的最高血清浓度为66毫克/毫升。该浓度比单个250mg口服片剂提供的浓度低约100倍。 在所有患者的大多数时间点，血清甲硝唑浓度均低于测定的可检测限。三名患者在任何时间点均未检测到甲硝唑的血清浓度。临床研究期间凝胶的平均剂量为600毫克，代表每次应用4.5毫克甲硝唑。 因此，在正常使用水平下，该制剂提供最低的甲硝唑血清浓度。Rosatan（甲硝唑）凝胶在治疗酒渣鼻中的作用机制尚不清楚，但似乎具有抗炎作用。
适应症和用途
Rosatan®（甲硝唑）凝胶可局部用于治疗酒渣鼻的炎症性丘疹和脓疱。
剂量和给药
每天早上和晚上两次将Rosadan（甲硝唑）凝胶薄膜涂抹并擦洗至整个患处。
在使用Rosadan®（甲硝唑）凝胶之前，应清洁待处理区域。 在使用Rosadan®（甲硝唑）凝胶后，患者可以使用化妆品。
禁忌症
具有甲硝唑，对羟基苯甲酸酯或其他配方成分过敏史的个人禁用Rosadan（甲硝唑）凝胶。
包装供应方式
Rosadan（甲硝唑）凝胶USP，0.75％装在45克试管中NDC 43538-182-45
储存条件
存放在20°-25°C（68°-77°F）[请参阅USP控制的室温]。
-------------------------------------------------- ROSADAN 0.75 % GEL 45GM METRONIDAZOLE MEDIMETRIKS PHARMA INC. 43538018245
使用以原处方为准； https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=99eaa138-0cfa-45e1-abbf-a88271707979
Rosadan(Metronidazole Gel USP, 0.75%)Gel and Rosadan(Metronidazole Topical Cream, 0.75%) Cream
Indicated for the treatment of inflammatory papules and pustules of rosacea
Specially developed formulas ideal for treating the face
Elegant formulations spread easily
Rosadan® Gel is engineered for patients with oily skin
Rosadan® Cream is engineered for patients who may benefit from additional emollients
Rosadan® Gel Kit Includes:
Rehyla® Wash
Unique cosmetic wash containing hyaluronic acid, chamomile and niacinamide
Gentle formula developed for patients with sensitive, irritated skin
Dermatologist-tested formulation is non-irritating
Dye, fragrance, paraben and sulfate free
May help reduce the appearance of redness
Offers unique conditioning properties
IMPORTANT SAFETY INFORMATION
Rosadan®(Metronidazole Topical Cream, 0.75%) and Rosadan® (Metronidazole Gel USP, 0.75%) are indicated for topical application in the treatment of inflammatory papules and pustules of rosacea. The following adverse events have been reported with the topical use of metronidazole: burning, stinging, erythema, skin irritation, pruritis and worsening of rosacea. Additional adverse experiences include dryness, transient redness, metallic taste, tingling or numbness of extremities and nausea. Rosadan® Cream and Rosadan® Gel are contraindicated in individuals with a history of hypersensitivity to metronidazole or any other ingredients in this formulation. Not for ophthalmic or vaginal use.
