EVOCLIN®（克林霉素磷酸酯）泡沫，1％ 用于局部使用
美国首次批准：1970
适应症和用法
EVOCLIN泡沫的适应症为治疗寻常痤疮患者12岁的年龄较大的治疗局部应用。
用法用量
EVOCLIN泡沫是用于局部使用的，并不用于口服，眼，或阴道内的使用。
每天使用一次EVOCLIN泡沫到灾区后，皮肤用温和的肥皂，让其充分干燥。使用足以覆盖整个受影响的区域。
如果一直没有起色后6〜8周或当条件变得更差，治疗应停药。
EVOCLIN泡沫的内容是易燃;避免火灾，在火焰和/或吸烟后立即应用。
剂型和规格
白色至灰白色耐热泡沫。每克EVOCLIN泡沫含有作为分配，12毫克克林霉素磷酸酯（1.2％），相当于克林霉素10毫克（1％）。
包装规格/储存与处理
如何供应
EVOCLIN泡沫含有相当于每克10毫克克林霉素磷酸酯，为白色至灰白色的颜色和不耐热。它可在以下尺寸：
•百克气雾罐 - NDC 0145-0061-00
•50克气雾罐 - NDC 0145-0061-50
存储和处理
在储存在68°F控制室内温度77°F（20°C至25°C）。
IMPORTANT SAFETY INFORMATION
Full Prescribing Information
EVOCLIN® (clindamycin phosphate) Foam, 1% is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, or a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis, including pseudomembranous colitis.
Prescribe with caution in atopic individuals.
Concomitant topical acne therapy should be used with caution since a possible cumulative irritancy may occur, especially with the use of peeling, desquamating, or abrasive agents. If irritation or dermatitis occurs, EVOCLIN Foam should be discontinued.
Diarrhea, bloody diarrhea, and pseudomembranous colitis have been reported with systemic and rarely with topical clindamycin. Discontinuation is recommended if significant diarrhea develops.
In clinical trials, the most common adverse events were headache (3%) and application-site reactions, including burning (6%), itching (1%), and dryness (1%).
The contents of EVOCLIN Foam are flammable; patients should avoid fire, flame, and/or smoking during and immediately following application.