部分中文凯思立处方资料（仅供参考）
产品名称：
凯思立d calcichew d3
成　　分：
本品每片含主要成份碳酸钙1.25克(相当于钙0.5克)，维生素D3200国际单位。 辅料为山梨醇、PVP K30、橘味颗粒、阿斯巴甜和硬脂酸镁。
适 应 症：
用于防治骨质疏松，也可作为儿童、妊娠、哺乳期妇女、更年期妇女、老年人等的钙补充剂。
用法用量：
咀嚼后咽下。成人，～次一片，一日一至二次，一日最大量不超过3片；儿童， 一次半片，一日一至二次。个别情况请遵医嘱。 
不良反应：
1．嗳气、便秘。
2．大剂量服用可发生高钙血症。
3．偶可发生奶一碱综合症，表现为高血钙、碱中毒及肾功能不全。 
注意事项：
1．心肾功能不全者慎用。
2．尿钙或血钙浓度过高者禁用。
3．洋地黄化病人禁用。
4．当药品性状发生改变时禁止服用。
5．儿童必须在成人监护下使用。
6．请将此药品放在儿童不能接触的地方。 
药物相互作用：
钙是维持人体神经、肌肉、骨骼系统、细胞膜和毛细血管通透性正常功能所必需，特别是对牙齿、骨骼的生长发育尤为重要。维生素D能参与钙和磷的代谢．能辅助“钙结合蛋白”的形成，进而使肠道中吸收钙送至血液及骨骼等组织。 
贮　　藏：
遮光，密封保存。
Calcichew D3
Main use：Calcium/vitamin D deficiency
Active ingredient：Calcium carbonate, colecalciferol
How does it work?
This medicine contains two active ingredients, calcium carbonate, which is a calcium salt used mainly to supplement calcium in the diet, and colecalciferol, otherwise known as vitamin D3.
Calcium is needed for the formation of strong bones and healthy teeth and is involved in helping the blood to clot. It is also required to transmit nerve signals and help muscles work.
Calcium is found in milk and dairy products, as well as spinach, nuts and sardines. Usually, calcium requirements are met from the diet.
However, there are times when the amount of calcium required is increased, such as during pregnancy, when breast feeding or with advancing age. When there is insufficient calcium in the diet to meet the body's needs, supplements are needed, otherwise calcium deficiency can occur.
Calcium supplements are useful in osteoporosis; a calcium intake that is twice the recommended daily allowance (RDA) slows the rate of bone loss and reduces the risk of fractures.
Colecalciferol, also known as vitamin D3, is normally obtained primarily from sunlight acting on the skin. It is also consumed in the diet in oily fish and milk products. Vitamin D deficiency develops when there is inadequate exposure to sunlight, such as in elderly people with reduced mobility or who are housebound, or when there is a lack of the vitamin in the diet.
Vitamin D is needed for calcium to be absorbed from the gut, and deficiency can lead to low
calcium levels and subsequent weakening of bones.
This is known as osteomalacia. Vitamin D supplements correct vitamin D deficiency and improve calcium absorption from the gut.
Calcium and vitamin D supplements are used to treat osteomalacia and osteoporosis. By increasing vitamin D and calcium in the body they help strengthen the bones. They are also used to supplement the diet during pregnancy, when there are increased requirements for these nutrients.
Calcium and vitamin D supplements are also given to prevent and treat dietary deficiency, for example in the housebound elderly.
What is it used for?
Osteoporosis
Softening of the bones when there is lack of Vitamin D in the body
(osteomalacia)
Vitamin D and calcium deficiency
Vitamin D and calcium supplementation in pregnancy Warning!
If you have mild to moderate kidney failure or raised levels of calcium in your urine (hypercalciuria) the amount of calcium in your blood and urine should be regularly monitored while you are taking this medicine.
If you have a history of kidney stones, the amount of calcium excreted in your urine should be monitored while you are taking this medicine.
It is recommended that people receiving long-term treatment with this medicine are monitored for the amount of calcium in their blood and urine, and their kidney function.
Use with caution in
Decreased kidney function High levels of calcium in the urine (mild hypercalciuria) History of kidney stones (nephrolithiasis)
Not to be used in
Children under 12 years of age
High levels of calcium in the blood (hypercalcaemia)
Kidney stones (nephrolithiasis)
Osteoporosis caused by prolonged immobilisation, eg due to paralysis of the legs Severe kidney failure Very high levels of calcium in the urine (severe hypercalciuria) This medicine should not be used if you are allergic to one or any of its ingredients.
Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding.
However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if
you are pregnant or planning a pregnancy, before using any medicine.
This medicine may be used during pregnancy and breastfeeding, as calcium and vitamin D requirements are increased in these cases.
However, you should only use this medicine after consulting your doctor.
Label warnings
This medication is to be sucked or chewed.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine.
Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Constipation
Diarrhoea
Pain in the stomach and abdominal area Excess gas in the stomach and intestines (flatulence)
Nausea
Skin rashes
High blood calcium level (hypercalcaemia) High calcium levels in the urine The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
Calcium salts may reduce the absorption from the gut of the following medicines:
- tetracycline-type antibiotics, eg tetracycline, doxycycline, minocycline
- some quinolone-type antibiotics, eg ciprofloxacin, norfloxacin
- iron preparations
- bisphosphonates, eg etidronate
- thyroxine
- sodium fluoride.
To avoid the calcium stopping these medicines from being adequately absorbed, the calcium dose should be separated from these medicines by at least four hours.
If the amount of calcium in the blood becomes too high, it may enhance the effect on the heart of digoxin or other cardiac glycosides.
Thiazide diuretics, eg bendrofluazide, can increase the amount of calcium in the body. If they are taken with calcium supplements this may therefore cause the calcium levels to rise too high.
The following medicines may reduce the effect of vitamin D:
- antiepileptic medicines, eg phenytoin
- barbiturates
- corticosteroids, eg hydrocortisone.
Other medicines containing the same active ingredientsAdcal D3 
Calcichew D3 Forte