部份中文氟比洛芬处方资料（仅供参考）
英文名：Ampiroxicam
商品名：Flucam Capsules
中文名：安吡昔康胶囊
生产商：辉瑞日本公司
药品简介
Flucam（Ampiroxicam）是环氧合酶抑制剂，为吡罗昔康的前体药物。临床用于慢性风湿性关节炎，变形性关节炎，腰痛症，肩关节周围炎，颈肩腕综合征的镇痛和消炎及外伤性疼痛，手术后及拔牙后的镇痛消炎。
フルカムカプセル13.5mg/フルカムカプセル27mg
药效分类名称
镇痛剂/抗炎剂
批准日期：1994年1月
商品名
Flucam Capsules 13.5mg
Flucam Capsules 27mg
一般的名称
アンピロキシカム（Ampiroxicam）
化学名
Ethyl（1RS）-1-（｛2-methyl-1,1-dioxido-3-［（pyridin-2-ylamino）carbonyl］-2H-1,2-benzothiazin-4-yl｝oxy）ethyl carbonate
分子式
C20H21N3O7S
分子量
447.46
性状
它是一种白色至黄白色结晶粉末。
它易溶于乙酸 (100)，微溶于乙腈，极难溶于乙醇 (99.5)，几乎不溶于水。
乙腈溶液 (1 → 20) 不显示旋光。
化学構造式
融点
約156℃（分解）
药效药理
作用机制
氨吡昔康在口服后从肠道吸收的过程中转化为吡罗昔康。这种活性体吡罗昔康的作用被认为是由于抑制花生四烯酸代谢中的环氧合酶和抑制与炎症和疼痛有关的前列腺素生物合成。
抗炎作用
氨吡昔康对卡拉胶植物性水肿（大鼠）的抑制作用与吡罗昔康几乎相同，略强于阿西美辛。氨吡昔康与吡罗昔康一样有效，并且对瘀伤水肿（大鼠）和紫外线红斑（豚鼠）的作用强于阿西美辛。它通过棉球法对肉芽（大鼠）和佐剂性关节炎（大鼠）等亚急性/慢性炎症表现出与吡罗昔康相同的抗炎作用。
镇痛作用
氨吡昔康对醋酸裂解（小鼠）的抑制作用与吡罗昔康和阿西美辛相似。大鼠足垫对炎症性疼痛的抑制作用（Randall-Selitto 方法）与吡罗昔康和阿西美辛相当。对辅助性关节痛（大鼠）的镇痛作用也与吡罗昔康和阿西美辛相似。
适应症
下列疾病和症状的镇痛消炎
类风湿关节炎
骨关节炎
腰背疼痛
肩周炎
颈肩臂综合征
用法与用量
一般而言，对于成人，每天一次饭后口服27毫克氨吡昔康。
应根据年龄和症状减少剂量。
包装
胶囊
13.5毫克：100粒[10粒 (PTP) x10]
27毫克：100粒[10粒(PTP) x 10]
制造商和分销商
辉瑞日本公司
注：以上中文处方资料不够完整，使用者以原处方资料为准。
完整说明资料附件：
https://www.info.pmda.go.jp/go/pack/1149030M1027_4_03/
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Flucam Capsules 13.5mg（フルカムカプセル13.5mg）
Brand name : Flucam Capsules 13.5mg
　Active ingredient: Ampiroxicam
　Dosage form: pale yellow capsule, diameter 5.1 mm, length 14.2 mm
　Print on wrapping: フルカム13.5mg, FLUCAM13.5mg, FC13.5
Effects of this medicine
This medicine inhibits production of prostaglandin (substance that induces inflammation or enhances the pain), thus relieves joints or muscle pain by suppress the inflammation and swelling.
Usually, used for anti-inflammation/relieve pain such as rheumatoid arthritis, osteoarthritis, low back pain, periarthritis scapulohumeralis, cervico-omo-brachial syndrome.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: peptic ulcer, hematological disorder, hepatic impairment, renal impairment, aspirin asthma or history of it, cardiac dysfunction, hypertension, bleeding tendency, bronchial asthma.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
In general, for adults, take 1 capsule (27mg of the active ingredient) once a day after meal. The dose should be adjusted according to your disease, age and symptoms. The maximum daily dose is up to 1 capsule (27 mg). Strictly follow the instructions.
If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include pain or discomfort in the stomach/abdomen, swelling, rash, photosensitivity, itch, eczema, rubor and hives. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
abdominal pain, vomiting, hematemesis/melena [peptic ulcer, gastrointestinal bleed]
breathing difficulty, generalized hot flash, hives [shock, anaphylactoid symptom]
high fever, redness of skin, stomatitis [Stevens-Johnson syndrome, toxic epidermal necrosis]
decreased urine output, swelling, headache [acute renal failure]
symptoms of anemia, bleeding tendency, fever [aplastic anemia, myelosupression]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
?Discard the remainder. Do not store them.
Pfizer Pharmaceuticals Inc.Internal
Revised: 11/2009
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions(risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.