What is it and how is it used?
Resolor belongs to a group of gut motility enhancing medicines (enterokinetics). It acts on the muscle wall of the gut, helping to restore the normal functioning of the bowel. The tablets are used for the treatment of chronic constipation in women in whom laxatives do not work well enough.

Not for use in men, children and adolescents younger than 18 years as Resolor has been insufficiently studied in these populations.

What do you have to consider before using it?
Do not take Resolor if you:

are allergic (hypersensitive) to prucalopride or any of the other ingredients of Resolor,
are on renal dialysis,
suffer from perforation or obstruction of the gut wall, severe inflammation of the intestinal tract, such as Crohn’s disease, ulcerative colitis or toxic megacolon/megarectum.
Take special care with Resolor if you:

suffer from severe kidney disease,
suffer from severe liver disease,
are currently under supervision by your doctor for a serious medical problem such as lung or heart disease, cancer or AIDS.
If you have very bad diarrhoea, the contraceptive pill may not work properly and the use of an extra method of contraception is recommended. See the instructions in the patient leaflet of the contraceptive pill you are taking.

Taking other medicines
Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Taking Resolor with food and drink
Resolor can be taken with or without food and drinks, at any time of the day.

Pregnancy and breast-feeding
Do not take Resolor if you are pregnant or if you intend to become pregnant unless your doctor advises you to do so.

When breast-feeding, prucalopride can pass into breast milk. Do not use Resolor while breastfeeding unless your doctor advises you to do so.

Ask your doctor for advice before taking any medicine.

Driving and using machines
Resolor is unlikely to affect your ability to drive or use machines. However, sometimes Resolor may cause dizziness and tiredness, especially on the first day of treatment, and this may have an effect on driving and use of machines.

Important information about some of the ingredients of Resolor
Resolor contains lactose monohydrate. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

How is it used?
Always take Resolor exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. You must take Resolor every day for as long as your doctor prescribes it.

The doctor may want to reassess your condition and the benefit of continued treatment after the first 4 weeks and thereafter at regular intervals.

The usual dose of Resolor for most patients is one 2 mg tablet once a day.

If you are older than 65 years, the starting dose is one 1 mg tablet once a day, which your doctor may increase to 2 mg once a day if needed.

Your doctor may also recommend a lower dose of one 1 mg tablet daily if you have severe kidney or liver disease.

Taking a higher dose than recommended will not make the product work better.

Resolor is only for adult women and should not be taken by children and adolescents up to 18 years.

If you take more Resolor than you should
It is important to keep to the dose as prescribed by your doctor. If you have taken more Resolor than you should, it is possible that you will get diarrhoea, headache and/or nausea. In case of diarrhoea, make sure that you drink enough water.

If you forget to take Resolor
Do not take a double dose to make up for a forgotten tablet.

If you stop taking Resolor
If you stop taking Resolor, your constipation symptoms may come back again.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

What are possible side effects?
Like all medicines, Resolor can cause side effects, although not everybody gets them. The side effects mostly occur at the start of treatment and usually disappear within a few days with continued treatment.

The frequency of possible side effects listed below is defined using the following convention:

very common (affects more than 1 user in 10)
common (affects 1 to 10 users in 100)
uncommon (affects 1 to 10 users in 1,000)
rare (affects 1 to 10 users in 10,000)
very rare (affects less than 1 user in 10,000)
not known (frequency cannot be estimated from the available data).
The following side effects have been reported very commonly: headache, feeling sick, diarrhoea and abdominal pain.

The following side effects have been reported commonly: dizziness, vomiting, disturbed digestion (dyspepsia), rectal bleeding, windiness, abnormal bowel sounds, increase in frequency of passing urine (pollakiuria), tiredness.

The following uncommon side effects have also been seen: loss of appetite, tremors, pounding heart, fever and weakness. If pounding heart occurs, please tell your doctor.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

How should it be stored?
Keep out of the reach and sight of children.

Do not use Resolor after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month.

Store in the original blister package in order to protect from moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.