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Mitsubishi Tanabe Pharma Corporation
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The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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Brand name :
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KREMEZIN Fine Granules 2g
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Active ingredient:
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Spherical carbon adsorbent obtained by oxidizing and reducing spherical activated carbon at high temperature, which is derived from hydrocarbon from petroleum.
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Dosage form:
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black fine granules
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Print on wrapping:
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慢性腎不全用剤, クレメジン細粒分包2g, KREMEZIN, 2g
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Effects of this medicine
This medicine adsorbs uremic toxins and the precursor in the gastrointestinal tract in patients with chronic renal failure, so that they are excreted in the feces. This alleviates uremic symptoms such as loss of appetite, bad breath, nausea and itchiness, and also delays initiation of dialysis.
It is usually used to alleviate uremic symptoms and delay dialysis initiation in patients with progressive chronic renal failure.
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Before using this medicine, be sure to tell your doctor and pharmacist
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If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
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If you have transit disorder in the digestive tract.
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If you are pregnant or breastfeeding.
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If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
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Dosing schedule (How to take this medicine)
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Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
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In general, for adults, take 1 packet (2 g of the active ingredient) at a time, 3 times a day. Strictly follow the instructions.
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If you are currently taking any other medicines, do not take them at the same time; you should wait more than 30 minutes to 1 hour to take this medicine after taking the other medicine. However, there may be differences in the effectiveness of medicines between individuals and between different medicines, so pay attention to the effects of the other medicine.
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If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
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If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
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Do not stop taking this medicine unless your doctor instructs you to do so.
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Precautions while taking this medicine
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Possible adverse reactions to this medicine
The most commonly reported adverse reactions include constipation, loss of appetite, nausea/vomiting, bloated feeling of the stomach, rash and itching. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
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Storage conditions and other information
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Keep out of reach of children. Keep in the room temperature. Store away from heat, moisture and direct sunlight.
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Discard the remainder. Do not store them.
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