|
Meiji Seika Pharma Co., Ltd.
|
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
|
|
Brand name :
|
LASERPHYRIN 100mg FOR INJECTION
|
|
 |
Effects of this medicine
This medicine gathers in and around tumor cells and reacts to laser light to exert an antitumor effect.
It is usually used to treat early-stage lung cancer, primary malignant brain tumor (only when surgical removal of the tumor is performed) and local failure after chemoradiotherapy or radiotherapy for esophageal cancer eligible for laser irradiation. Thus, this is a local treatment and is ineffective on non-irradiated laser site.
|
Before using this medicine, be sure to tell your doctor and pharmacist
-
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have porphyria.
-
If you are pregnant or breastfeeding.
-
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
|
Dosing schedule (How to take this medicine)
-
Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
-
Early-stage lung cancer, local failure after chemoradiotherapy or radiotherapy for esophageal cancer: In general, this medicine is injected once intravenously. The target lesion is then irradiated by laser light 4 to 6 hours after the injection.
Primary malignant brain tumor: In general, this medicine is injected once intravenously. The target lesion is then irradiated by laser light 22 to 26 hours after the injection.
-
The treatment period with this medicine is determined based on the response to the treatment. Ask the doctor about the treatment span.
|
Precautions while taking this medicine
-
In treatment of local failure in patients with esophageal cancer, dietary intake may cause intense inflammation and weakening of the tissues, resulting in esophageal perforation. For this reason, the patients should fast from the morning on the day of administration until the following day of laser irradiation and receive nutritional care with fluid replacement.
-
This medicine may cause photosensitivity. Avoid direct sunlight and stay in rooms conditioned at lighting intensity of 500 lux or less by using shade curtains for 2 weeks after the injection. Wear sunglasses for 3 days after the injection.
|
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include increased sputum, bloody sputum, cough, sore throat, fever and esophageal pain. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
-
breathing difficulty, shortness of breath on exertion [respiratory distress]
-
general malaise, loss of appetite, yellowing of the skin and the white of eyes [liver dysfunction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
|
|
