Effects of this medicine

Before using this medicine, be sure to tell your doctor and pharmacist

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  If you have bleeding (intracranial bleeding, gastrointestinal bleeding, etc.), liver disorder, renal disorder, acute bacterial endocarditis, bleeding tendency, prolonged bleeding or low body weight.
  If you are at high risk of bleeding (If you have recently had gastrointestinal tract ulcer, intracranial bleeding or cerebrospinal/eye surgery. If you have a history of bronchiectasis or lung bleeding. If you have gastric ulcer, duodenal ulcer, malignant tumor or hypertension).

• If you are pregnant, possibly pregnant or breastfeeding.

• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

• Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>

• In general, for adults, take 15 mg of the active ingredient at a time, once a day after meals. If you have renal disorder, the dosage may be decreased to 10 mg at a time, once a day. This preparation contains 10 mg of the active ingredient in a tablet. Strictly follow the instructions.

• If you miss a dose, take a missed dose as soon as possible. However, there should be 12 hours or more before the next scheduled dose. You should never take two doses at one time.

• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

• Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

• If you will receive dental treatment, endoscopic examination or surgery, make sure to inform your doctor in advance that you are taking this medicine. If you will receive treatment in other medical institutions or buy other medicines at pharmacies, etc., inform your doctor or pharmacist that you are taking this medicine.
• Pay attention not to get injured since this medicine lead to prolonged bleeding. If bleeding time is prolonged or the injury involves a large area, immediately contact your doctor.
• Avoid taking any food containg hypericum perforatum (St. John's wort), since it may diminish medicinal effects.

Possible adverse reactions to this medicine

• nausea, vomiting, headache [bleeding (gastrointestinal bleeding, intracranial bleeding, etc.)]
• nausea, dull, yellowing of the skin and the white of eyes [liver dysfunction, jaundice]
• coughing, bloody phlegm, breathing difficulty, shortness of breath, fever [interstitial lung disease]

Storage conditions and other information

• Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•  Discard the remainder. Do not store them.