Effects of this medicine

Before using this medicine, be sure to tell your doctor and pharmacist

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  If you have respiratory function disorder, bronchial asthma, heart failure, a history of convulsions, paralytic ileus, acute alcoholic poisoning, hemorrhagic colitis or bacterial diarrhea.

• If you are pregnant or breastfeeding.

• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

• Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>

• In general, for adults, take 5 to 40 mg as oxycodone hydrochloride (anhydride) at a time, twice a day (every 12 hours). The dosage may be adjusted according to your symptoms. In the beginning, take 5 or 10 mg at a time, twice a day (every 12 hours). If you have been treated with any other analgesic agents, the dosage of this medicine is properly decided with attention to adverse reactions in consideration of the dosage of other agents and the analgesic duration. Furthermore, the dosage is adjusted to provide the appropriate analgesic effect and to minimize the adverse reactions. This product contains 20 mg of oxycodone hydrochloride (anhydride) per tablet. Strictly follow the instructions.
• This medicine is not for use to treat pain that you only have once in a while (as needed).
• If you still have a pain or feel very sleepy, consult with your doctor.
• Swallow whole of a tablet without chewing. Do not split or crush a tablet.

• If you miss a dose, take it as soon as you remember and continue your regular dosing schedule. You should never take two doses at one time.

• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

• Do not stop taking this medicine unless your doctor instructs you to do so. Sudden discontinuation of taking this medicine may cause adverse events.

Precautions while taking this medicine

• Since this medicine may cause drowsiness or dizziness, avoid driving a car or operating dangerous machinery.
• Alcohol may enhance the effects or the adverse reactions of this medicine.
• If you are breastfeeding, avoid breastfeeding while taking this medicine.
• You may find an object in the shape of a tablet in your stool, however, there is no need to worry about it because this object is an empty shell remaining after the ingredients of this medicine are melted away.

Possible adverse reactions to this medicine

• facial pallor, breathlessness, swelling around eyes and/or mouth (lips)  [shock, anaphylaxis]
• desire for the medicine even when taking the medicine is not needed  [dependence]
• breathlessness, shortness of breath  [depressed respiration]
• disoriented, speaking in tongues, feeling as if the thing which is not in fact were visible or audible  [confusion, delirium]
• constipation, feeling of fullness in abdomen, severe pain in abdomen  [paralytic ileus, toxic megacolon]

Storage conditions and other information

• Keep the medicine out of the reach of infants and children. Store it at room temperature (1 to 30 degrees Celsius) away from direct sunlight and moisture.
• Do not give the medicine to anyone else.
•  Return the remainder or the medicine which is no longer needed to your hospital or pharmacist.