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Meiji Seika Pharma Co., Ltd.
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The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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Brand name :
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ADANT DISPO INTRA-ARTICULAR INJECTION 25mg
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Active ingredient:
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Purified sodium hyaluronate
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Effects of this medicine
This medicine suppresses pain and inflammation of knee and shoulder joint, and improves the movements.
It is usually used to treat osteoarthritis of the knee, frozen shoulder and knee pain of rheumatoid arthritis.
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Before using this medicine, be sure to tell your doctor and pharmacist
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If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have or have previously experienced liver disorder.
If you have skin disease on injection site.
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If you are pregnant or breastfeeding.
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If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
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Dosing schedule (How to take this medicine)
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Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
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Osteoarthritis of the knee and frozen shoulder: In general, inject into a joint cavity of knee or a joint of shoulder once a week for five consecutive times.
Rheumatoid arthritis: In general, inject into a joint cavity of knee once a week for five consecutive times.
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The treatment period with this medicine depends on your symptoms or response to this medicine.
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Precautions while taking this medicine
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Possible adverse reactions to this medicine
The most commonly reported adverse reactions include injection site pain, injection site swelling, edema of knee on injection site, rash such as hives, itching, edema (edema of face/eyelid, etc) and facial redness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
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dizziness, facial pallor, loss of consciousness [shock]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
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Storage conditions and other information
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Keep at rest if you have joint pain after injection.
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Keep the injection site clean as much as possible.
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