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Manufacturer's name : JANSSEN PHARMACEUTICAL K.K. |
620005884 |
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Revised: 07/2008 |
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Brand name : |
PREZISTA Tablets 300mg |
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Active ingredient: |
Darunavir ethanolate |
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Dosage form: |
orange tablet, major axis 17.3 mm, minor axis 8.6 mm, thickness 5.5 mm |
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Printings on wrapping: |
TMC114 |
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Effects of this medicine
This medicine is a HIV-1 protease inhibitor that suppresses growth of human immunodeficiency virus (HIV) to slow progression of the infection. It is indicated for the treatment together with other HIV protease inhibitors (such as ritonavir) to have a synergetic effect. Ritonavir increases the blood level of this medicine.
Usually, used for treatment of HIV infection in combination with ritonavir and other anti-HIV agents. |
Before using this medicine, tell your doctor/pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you have liver dysfunction, hemophilia, or bleeding tendency.
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If you are pregnant or breastfeeding.
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If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)
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Dosage regimen (proper use of this medicine)
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Your dosage regimen is:(order of your doctor)
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General dosage regimen: For adults, take 2 tablets (600 mg of darunavir) twice daily with ritonavir 100 mg with or after meal. Strictly follow the instructions of your doctor/pharmacist.
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Missed dose: It is very important to continue taking this medication as prescribed. If you stop taking this medicine and ritonavir, the beneficial effects of these medicines may be reduced or even lost. If you miss a dose, skip the missed dose and take it at next meal. When you take the missed dose, take 2 tablets at a time as regular dosing schedule. Do not take 4 tablets at a time for daily dosage.
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Overdose: If you took too much of this medicine (more than ordered), check with your doctor/pharmacist.
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Others: Do not stop taking this medicine without the instructions of your doctor.
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Precautions while using this medicine
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Saint. John's wort may decrease the blood concentration of this medicine and reduce the effect of it. Avoid taking it with food or beverage containing Saint. John's wort (Hypericum perforatum).
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Floating dizziness have been reported to occur after taking this medicine. Be aware of driving a car or operating dangerous machinery.
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Side effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: diarrhea, vomiting.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop taking your medicine and check with your doctor immediately.
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high fever (38℃ or more), red eyes, erosive lips and mouth, red rash[mucocutaneous-ocular syndrome, erythema multiforme]
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general fatigue, loss of appetite, yellowing of the skin or whites of the eyes[liver dysfunction, jaundice]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom. |
Storage and other information
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Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
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Discard the remainder. Do not store them. If you dispose of unused medicines, seek advice of your pharmacist about proper disposal of drugs.
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For further information, ask your doctor/pharmacist. "Kanjamuke Iyakuhin Guide" and Japanese package insert information (for medical professionals) is available on the website of Pharmaceuticals and Medical Devices Agency. |
