Manufacturer's name : Takeda Chemical Industries, Ltd. |
620009091 |
Revised: 03/2010 |
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Brand name : |
ECARD Combination Tablets LD |
Active ingredient: |
Candesartan cilexetil |
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Hydrochlorothiazide |
Dosage form: |
very pale yellow oval tablets, major axis 8.6 mm, minor axis 5.1 mm, thickness 3.0 mm |
Printings on wrapping: |
(Face) エカードLD 293 (Back) エカードLD |
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Effects of this medicine
This medicine lowers blood pressure by reducing peripheral vascular resistance via antagonism against receptor for the pressor substance angiotensin II as well as by increasing urine output via inhibition of sodium and water reabsorption in the kidney.
Usually, used for treatment of hypertension. |
Before using this medicine, tell your doctor/pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you scarcely void urine; are on hemodialysis; or have electrolyte imbalance (abnormal blood sodium, potassium, calcium levels), renal disease, liver disorder, coronary arterial sclerosis, cerebral arterial sclerosis, diarrhea/vomiting, or hyperparathyroidism.
If you are on low-salt diet, in a post-sympathectomy state, in a preoperative state.
If you or any one among your parents and siblings have gout/diabetes mellitus.
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If you are pregnant or breastfeeding.
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If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)
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Dosage regimen (proper use of this medicine)
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Your dosage regimen is:(order of your doctor)
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For adults, take 1 tablet at a time, once a day. Strictly follow the instructions of your doctor/pharmacist.
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Missed dose: If you miss a dose, take the missed dose as soon as possible. However, let more than 8 hours pass before taking the next dose. DO NOT take double doses to make up for the missed dose.
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Overdose: If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
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Others: Do not stop taking the medicine without the instructions of your doctor.
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Precautions while using this medicine
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As dizziness and light-headedness may appear due to excessive lowering of blood pressure, take extra care when working at heights or operating dangerous machinery such as driving a car.
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Caution should be exercised as alcohol drinking may intensify orthostatic hypotension (dizziness on standing up).
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Side effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: rash, itching, photosensitivity, breathing difficulty, hot flush, dizziness, light-headedness, dizziness on standing up, palpitation, glow, extrasystoles, headache, nausea, stomatitis, taste abnormality, constipation, dry mouth, anemia, malaise, frequent urination, edema, cough, erectile dysfunction, abnormal vision, etc.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop taking your medicine and check with your doctor immediately.
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swelling of face/tongue/throat, breathlessness[angioedema]
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feeling cold, vomiting, loss of consciousness[shock, syncope, loss of consciousness]
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decreased urination output, swelling of face and hands/feet, fever[acute renal failure]
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numbness of hands/feet and lips, muscle weakness[hyperkalemia]
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dullness, loss of appetite, nausea[hyponatremia]
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yellowing of the skin or whites of the eyes, dullness, loss of appetite[liver dysfunction, jaundice]
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fever, sore throat, dullness[agranulocytosis]
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lassitude, muscle pain, brown urine [rhabdomyolysis]
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fever, dry cough, breathlessness[interstitial pneumonia, pulmonary edema]
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fever, muscle pain/arthralgia, facial erythema[exacerbation of systemic lupus erythematosus]
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cold sweat, feeling hungry, tremor in hands[hypoglycemia]
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bleeding tendency, purpura, fever[aplastic anemia, hemolytic anemia]
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bleeding tendency, purpura[necrotizing angiitis]
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numbness of hands/feet and lips, nausea[anaphylactic reaction]
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fever, dullness, rash[toxic epidermal necrolysis]
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fever, rash, joint pain[interstitial nephritis]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom. |
Storage and other information
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Keep out of the reach of children. Store away from heat and humidity.
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Discard the remainder. Do not store them.
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