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EPALRESTAT Tablets 50mg "TAKATA"£¨¥¨¥Ñ¥ë¥ì¥¹¥¿¥Ã¥ÈåV50mg¡¸¥¿¥«¥¿¡¹£©
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Internal
Published: 6/2012

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse effects (risks) as well as efficacies (benefits). It is important to minimize adverse effects and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
EPALRESTAT Tablets 50mg "TAKATA"
¡¡Active ingredient:
Epalrestat
¡¡Dosage form:
white tablet, φ 6.7mm, thickness 3.3mm
¡¡Print on wrapping:
¥¨¥Ñ¥ë¥ì¥¹¥¿¥Ã¥È50mg¡¸¥¿¥«¥¿¡¹, TTS-275, 50mg, EPALRESTAT 50mg ¡¸TAKATA¡¹, ¥¨¥Ñ¥ë¥ì¥¹¥¿¥Ã¥È, ʳǰ¤Ë·þÓÃ

Effects of this medicine

This medicine suppresses accumulation of sorbitol in nerve by inhibiting aldose reductase, and relieves numbness/pain of the hands and feet and leg cramp, etc., which induced by diabetic peripheral neuropathy.
It is usually used to treat diabetic peripheral neuropathy.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>
  •  
  • In general, for adults, take 1 tablet (50mg of the active ingredient) at a time, three times daily, before meal. The dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
  • If you miss a dose, take as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • If you find your urine yellowish brown or reddish after taking the medicine, take it as usual, because the yellowish brown or reddish color is attributed to components of this medicine.
  •  

Possible adverse effects of this medicine

The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse effects indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • nasal/gum bleeding, subcutaneous bleeding in limbs[thrombocytopenia]
  • generalized fatigability, nausea, yellowness in skin or conjunctiva[fulminant hepatitis, liver dysfunction, jaundice, liver failure]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  •  Discard the remainder. Do not store them.
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