Effects of this medicine

Before using this medicine, be sure to tell your doctor and pharmacist

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  If you have diabetes or if you or your family has a history of diabetes.
  If you have hepatic disorder, cardiovascular disease or hypotension.
  If you have a convulsive disease such as epilepsy, or a history thereof.
  If you have suicidal attempt or suicidal ideation.
  If you have a predisposition to organic brain disorder.
  If you have a highly impulsive comorbid disorder.

• If you are pregnant or breastfeeding.

• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

• Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>

• For schizophrenia: In general, for adults, start with taking 6 to 12 mL (6 to 12 mg of the active ingredient) daily, then take 6 to 24 mL (6 to 24 mg of the active ingredient) daily at one time or in two divided doses as a maintenance dose. The dosage may be adjusted according to age and symptoms. However, the daily dose should not exceed 30 mL (30 mg of the active ingredient).
  For improvement of manic episodes associated with bipolar disorder: In general, for adults, take 12 to 24 mL (12 to 24 mg of the active ingredient) at one time, once daily. The starting dose is determined as 24 mL (24 mg of the active ingredient), and the dosage may be adjusted according to age and symptoms. However, the daily dose should not exceed 30 mL (30 mg of the active ingredient).
  For depression/depressive state (administration should be limited to patients who showed an inadequate response to existing antidepressant therapy.): In general, for adults, take 3 mL (3 mg of the active ingredient) at one time, once daily. The dosage may be adjusted according to age and symptoms. The dose increase per day should be 3 mL (3 mg of the active ingredient). However, the daily dose should not exceed 15 mL (15 mg of the active ingredient).
  This preparation contains 6 mL (6 mg of the active ingredient) in a sachet. In any case, strictly follow the instructions.
• You may take a dose of this medicine as it is or put it in a cup of (approx. 150 mL) warm water, cooled boiled water or juice and mix it, then take the mixture as soon as possible after dissolving. Never use unboiled water, beverages derived from tea leaves (black tea, oolong tea, green tea, brown rice tea, etc.) and bean paste soup (miso soup) to dissolve since the medicinal content may be reduced. In addition, when you mix this medicine with some water that has a high mineral content, sometimes you may find that the mixture is turbid. In this case, you should not take it since the medicinal content may be reduced.

• If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.

• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

• Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

• This medicine may cause sleepiness; decreased attentiveness, concentration and reflex movements. Avoid operating dangerous machinery such as driving a car.
• Alcohol may intensify the therapeutic effects of the medicine. Be careful when drinking alcohol.

Possible adverse effects of this medicine

• dry mouth, excessive intake of water, increased urine output [diabetic ketoacidosis, diabetic coma]
• being silent without moving, muscle stiffness, sudden fever [neuroleptic malignant syndrome]
• involuntary movement around the mouth (moving the tongue, continual movement of the mouth appearing to chew something) [tardive dyskinesia]
• nausea, vomiting, constipation, intense abdominal pain [paralytic ileus]
• weakness, muscle pain, reddish brown urine [rhabdomyolysis]

Storage conditions and other information

• Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
•  If there is a remainder, this is to be discarded. Do not store it. Ask the pharmacy or medical institution about how to discard the remainder.