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ENBREL 50mg Syringe 1.0mL for S.C. Injection
2014-04-06 07:34:31 来源: 作者: 【 】 浏览:465次 评论:0
Manufacturer's name : Takeda Chemical Industries, Ltd. 622003901
Newly-created: 10/2010
 
Brand name : ENBREL 50mg Syringe 1.0mL for S.C. Injection
 Active ingredient: Etanercept (genetical recombination)
 Dosage form: colorless to clear pale yellow injectable preparation in syringe
 Printings on wrapping:  

Effects of this medicine

This medicine suppresses action of TNF, a cytokine in the body, which is considered to be a primary factor that is related to immune mechanism and onset of inflammation and pain and progress in rheumatoid arthritis.
Usually, used for treatment of rheumatoid arthritis.

Before using this medicine, tell your doctor/pharmacist

  • If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you have infection, tuberculosis, demyelinating disorders such as multiple sclerosis, optic nerve inflammation or its past history, congestive heart failure, blood disorders or its past history, a history of interstitial pneumonia, cancer or its past history.
    If you have received live vaccines (such as rubella/mumps vaccines) just before use of the medicine.
  • If you are pregnant or breastfeeding.
  • If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)

Dosage regimen (proper use of this medicine)

  • Your dosage regimen is:(order of your doctor)
  •  
  • General dosage regimen: For adults, subcutaneously inject 1 syringe (50 mg of the active ingredient) once a day, once a week. Strictly follow the instructions of your doctor/pharmacist.
  • The contents of a syringe should be used all at once.
  • Avoid injection to the site overlapped to previously injected sites (Inject the medicine at least 3 cm apart from the previous injected site).
  • Do not massage the injected site after giving the injection.
  • Patients can self-inject the medicine (self injection), only if the doctor has confirmed that patient meets certain criteria for the self-injection.
  • Missed dose: If you missed an injection, check with your doctor/pharmacist or nurse.
  • Overdose: If you used too much of the medicine (more than ordered), check with your doctor/pharmacist.
  • Others: Do not stop your medication without the instructions of your doctor.

Precautions while using this medicine

  • Do not receive live vaccines (such as rubella/mumps vaccines) because of infection risk of the virus. If you will receive live vaccines for prevention, inform your doctor that you are using the medicine and consult with him or her.
  •  

Side effects of this medicine

Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: injection site reactions (red spot, swelling, pain, itching), dizziness, etc. Most of these symptoms will recover spontaneously for 2-3 days. Do not scratch or touch the injection site. If a severe swelling or pain is observed, consult with doctor, pharmacist or nurse.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop taking your medicine and check with your doctor immediately.
  • sudden high fever with chill and trembling, blood pressure decrease[sepsis]
  • persistent slight fever, persistent cough (for more than 2 weeks), dullness (general)[tuberculosis including extrapulmonary tuberculosis]
  • fever, dullness (general), breathlessness[pneumonia, opportunistic infection]
  • redness (general), swelling (general), breathlessness[serious allergic reactions]
  • persistent fever, sore throat, paleness of the face [serious blood disorders]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom.

Storage and other information

  • Keep out of the reach of children. Store at 2-8℃ and avoid light and freezing.
  • Discard the remainder. Do not store them. If you dispose of unused medicines, seek advice of your pharmacist about proper disposal of drugs.
For further information, ask your doctor/pharmacist. "Kanjamuke Iyakuhin Guide" and Japanese package insert information (for medical professionals) is available on the website of Pharmaceuticals and Medical Devices Agency. 
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