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Manufacturer's name : Takeda Chemical Industries, Ltd. |
621986001 |
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Revised: 08/2010 |
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Brand name : |
NESINA Tablets 6.25mg |
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Active ingredient: |
Alogliptin benzoate |
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Dosage form: |
light red oval tablets, major axis 10.1 mm, minor axis 5.1 mm, thickness about 3.4 mm |
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Printings on wrapping: |
(Face) ネシーナ 6.25mg 385, (Back) ネシーナ 6.25 |
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Effects of this medicine
This medicine inhibits the enzyme (DPP-4) which catalyzes decomposition of incretin, a hormone acting to maintain constant blood glucose level.
It stimulates insulin secretion when blood glucose level is elevated and suppresses glucagon secretion to improve blood glucose control.
Usually, used for treatment of type II diabetes mellitus. |
Before using this medicine, tell your doctor/pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you have severe ketosis, diabetic coma or precoma, insulin-dependent diabetes mellitus, or severe infection; are in a pre- or post-operative state; have a serious injury, renal disorder, heart failure, pituitary abnormality, adrenal disorder, or inadequate food intake; or are debilitated, doing strenuous physical exercises, or a heavy drinker.
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If you are pregnant or breastfeeding.
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If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)
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Dosage regimen (proper use of this medicine)
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Your dosage regimen is:(order of your doctor)
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General dosage regimen: for adults, take 4 tablets (25 mg of alogliptin) at a time, once a day. The dosage is to be reduced according to degree of existing renal function in patients with moderate or severer renal dysfunction. Strictly follow the instructions of your doctor/pharmacist.
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Missed dose: If you missed a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
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Overdose: If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
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Others: Do not stop taking the medicine without the instructions of your doctor.
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Precautions while using this medicine
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Strictly adhere to dietary instructions given and to kinesitherapy prescribed.
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Much caution should be exercised as hypoglycemia may occur.
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When hypoglycemia symptoms occur, take an adequate amount of sugar (e.g., sugar, glucose,
soft drinks). If you are taking the medicine concomitantly with an α-glucosidase inhibitor (drugs which delay absorption of sugar such as voglibose and acarbose), ingest glucose in case of any hypoglycemic symptoms.
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Side effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: rash, enlarged feeling of abdomen, abdominal pain, gastroenteritis, constipation, headache, dizziness, numbness of hands/feet, malaise, nasopharyngitis, swelling, palpitation, arthralgia, muscle pain, etc. In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop taking your medicine and check with your doctor immediately.
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cold sweat, hungry feeling, tremor in hands/feet[hypoglycemia]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom. |
Storage and other information
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Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
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Discard the remainder. Do not store them.
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For further information, ask your doctor/pharmacist. "Kanjamuke Iyakuhin Guide" and Japanese package insert information (for medical professionals) is available on the website of Pharmaceuticals and Medical Devices Agency. |
