Effects of this medicine

Before using this medicine, be sure to tell your doctor and pharmacist

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  If you have: hypotension, hepatic or renal dysfunction.

• If you are pregnant, possible pregnant or breastfeeding.

• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

• Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>

• For hypertension: In general, for adults, take 0.5 to 1 tablet (2.5-5 mg of amlodipine) at a time, once daily. The dosage may be adjusted according to the symptoms, however, if the effect is insufficient, the dosage may be increased up to 2 tablets (10 mg), once daily. In general, for children aged 6 years and older, take 0.5 tablet (2.5 mg) at a time, once daily. The dosage may be adjusted according to the age, body weight and symptoms, however, the maximum daily dose is 1 tablet (5 mg).
  For angina pectoris: In general, for adults, take 1 tablet (5 mg of amlodipine) at a time, once daily. The dosage may be adjusted according to the symptoms.
  Strictly follow the instructions in any case.
• This medicine is orally disintegrating tablet. Take this medicine in either of the following ways:
  (1) Take this medicine with water or warm water as you do an ordinary tablet.
  (2) Soak the tablet with saliva on your tongue and crush it lightly with your tongue, then swallow it with saliva. However, never take the tablet without water when you are in a lying position.

• If you are a patient with hypertension and miss a dose, it is all right if you skip the missed dose. Follow your regular dosing schedule from the next day. If you are a patient with angina pectoris and miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose (approx. 8 hours), skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.

• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

• Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

• This medicine may cause dizziness or lightheadedness due to decreasing of blood pressure. Pay close attention when you work at heights, drive a car or operate dangerous machinery.
• Grapefruit juice may intensify the antihypertensive action of this medicine. Do not take this medicine concomitantly with grapefruit juice.

Possible adverse effects of this medicine

• general malaise, yellowing in skin or white of eye, loss of appetite [hepatic dysfunction, jaundice]
• nasal bleeding, bleeding tendency, fever, throat pain [thrombocytopenia, leukopenia]
• shortness of breath, dizziness, faint [atrioventricular block]

Storage conditions and other information

• Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
• Discard the remainder. Do not store them. Ask the pharmacist how to discard them.
•  Take split tablet as soon as possible. If you store this medicine from necessity after splitting, store away from moisture and light.