Astellas Pharama Inc.
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The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse effects (risks) as well as efficacies (benefits). It is important to minimize adverse effects and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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Brand name :
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Irribow Tablets 2.5mcg
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Dosage form:
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light yellow tablet (φ: 5.6mm, thickness: 3.0mm)
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Print on wrapping:
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(Face) イリボー2.5μg, house-mark + astellas, (Back) house-mark + astellas, イリボー, 2.5μg, 下痢型過敏性腸症候群治療剤
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Effects of this medicine
This medicine improves diarrhea by exerting an opposing effect on serotonin 5-HT3 receptors on the efferent nerves and improves abdominal pain by exerting an opposing effect on serotonin 5-HT3 receptors on the afferent nerves.
It is usually used for the treatment of diarrhoea-predominant irritable bowel syndrome in males.
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Before using this medicine, be sure to tell your doctor and pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you have a history of abdominal operations.
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If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
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Dosing schedule (How to take this medicine)
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Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
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General dosage regimen: For male adults, take 2 tablets (5mcg of the active ingredient) at a time, once daily. The dose may be adjusted according to your symptoms. However, the maximum daily dose should not exceed 4 tablets (10mcg). Strictly follow the instructions of your doctor/pharmacist.
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If you have missed a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
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If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
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Do not stop taking the medicine without the instructions of your doctor.
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Precautions while taking this medicine
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Possible adverse effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: constipation, hard faeces, etc.
If there is no bowel movement for three consecutive days or longer, stop taking the medicine temporarily and consult with your doctor/pharmacist about the subsequent use of the medicine.
The symptoms described below are rarely seen as initial symptoms of the adverse effects indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
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facial pallorl, cold sweat, dizziness on standing up [shock, anaphylactoid symptoms]
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sudden abdominal pain, bloody stools, fever [ischaemic colitis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
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Storage conditions and other information
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Keep out of the reach of infants and children. Store away from direct sunlight, heat and humidity.
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Discard the remainder. Do not store them. Consult with your dispensing pharmacy when you discard the medicine.
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