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See related Navoban information |
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Manufacturer |
Novartis |
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Distributor |
Hong Kong: Zuellig/Macau: Four Star |
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Contents |
Tropisetron HCl |
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Indications |
Prevention of nausea & vomiting induced by cancer chemotherapy. Treatment & prevention of post-op nausea & vomiting, esp in patients undergoing intra-abdominal gynecological surgery.
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Dosage |
Prevention of nausea & vomiting induced by cancer chemotherapy Adult 6-day courses w/ one 5 mg/5 mL amp IV on day 1 & 1 cap/day on days 2-6. Childn >2 yr 0.2 mg/kg up to a max of 5 mg/day IV on day 1 & orally (amp soln diluted in orange juice or cola) on days 2 up to 6. Post-op nausea & vomiting Adult 2 mg by IV infusion or slow inj.
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Overdosage |
View Navoban overdosage for action to be taken in the event of an overdose. |
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Administration |
Should be taken on an empty stomach (Take in the morning immediately upon rising 1 hr before breakfast.). |
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Contraindications |
Pregnancy, unless surgical procedure involves therapeutic abortion.
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Special Precautions |
In uncontrolled HTN; cardiac patients; lactation, when patients drive a vehicle or operate machinery.
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Adverse Drug Reactions |
Headache, constipation. Less frequently, dizziness, fatigue, abdominal pain & diarrhea. Rarely, hypersensitivity reactions. Very rarely, collapse, syncope or CV arrest.
View ADR Monitoring Form |
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Drug Interactions |
Rifampicin, other liver enzyme-inducing drugs, that are likely to prolong the QTc interval.
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Storage |
View Navoban storage conditions for details to ensure optimal shelf-life. |
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Description |
View Navoban description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Navoban mechanism of action for pharmacodynamics and pharmacokinetics details. |
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