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See related Tygacil powd for inj information |
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Manufacturer |
Pfizer |
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Distributor |
Hong Kong: Zuellig/Macau: LF Asia (Macao) |
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Contents |
Tigecycline |
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Indications |
Treatment of complicated skin & skin structure infections, complicated intra-abdominal infections & community-acquired bacterial pneumonia in patients ≥18 yr.
Click to view Tygacil detailed prescribing infomation |
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Dosage |
Initially 100 mg, followed by 50 mg 12 hrly by IV infusion over approx 30-60 min. Complicated skin & skin structure infections, complicated intra-abdominal infections Treatment duration: 5-14 days. Community-acquired bacterial pneumonia Treatment duration: 7-14 days. Severe hepatic impairment 100 mg, followed by 25 mg 12 hrly.
Click to view Tygacil detailed prescribing infomation |
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Overdosage |
View Tygacil overdosage for action to be taken in the event of an overdose. |
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Contraindications |
Hypersensitivity. Childn <8 yr.
Click to view Tygacil detailed prescribing infomation |
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Special Precautions |
Hypersensitivity to tetracyclines. All-cause mortality. Anaphylaxis/anaphylactoid reactions. Severe hepatic impairment. Acute pancreatitis. Associated w/ tooth discoloration. Clostridium difficile associated diarrhea. Complicated intra-abdominal infections secondary to clinically apparent intestinal perforation. Overgrowth of nonsusceptible organisms may occur. Pregnancy & lactation. Childn <18 yr. Elderly.
Click to view Tygacil detailed prescribing infomation |
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Adverse Drug Reactions |
Abdominal pain, abscess, asthenia, headache, infection, phlebitis, diarrhea, dyspepsia, nausea, vomiting, anemia; increased alkaline phosphatase, amylase, BUN, SGOT & SGPT; bilirubinemia, abnormal healing, hypoproteinemia, dizziness, rash.
View ADR Monitoring Form |
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Drug Interactions |
Warfarin, OCs.
View more drug interactions with Tygacil |
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Pregnancy Category (US FDA) |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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Storage |
View Tygacil storage conditions for details to ensure optimal shelf-life. |
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Description |
View Tygacil description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Tygacil mechanism of action for pharmacodynamics and pharmacokinetics details. |
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Presentation/Packing |
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Form |
Packing |
Photo |
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Tygacil powder for injection |
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Tygacil (vial) 50 mg x 10's |
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Manufacturer: |
Pfizer |
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Distributor: |
Hong Kong: Zuellig
Macau: LF Asia (Macao)
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