See related Cubicin powd for inj information
Manufacturer AstraZeneca
Distributor Hong Kong: Zuellig/Macau: Four Star
Contents Daptomycin
Indications Treatment of complicated skin & skin structure infections (cSSSI) caused by susceptible isolates of the following gm+ve microorganisms: S. aureus (including methicillin-resistant isolates), Strep pyogenes, Strep agalactiae, Strep dysgalactiae subsp equisimilis & Enterococcus faecalis (vancomycin-susceptible isolates only); S. aureus bloodstream infections (bacteremia), including right-sided endocarditis caused bymethicillin-susceptible & -resistant isolates.
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Dosage cSSSI 4 mg/kg by IV infusion in 0.9% NaCl inj over a 30-min period once every 24 hr for 7-14 days. S. aureus bloodstream infections 6 mg/kg by IV infusion in 0.9% NaCl inj over a 30-min period once every 24 hr for a min of 2-6 wk. Patient w/ renal impairment CrCl <30 mL/min, including those on hemodialysis or CAPD 4 mg/kg (cSSSI) or 6 mg/kg (S. aureus bloodstream infections) once every 48 hr.
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Overdosage View Cubicin overdosage for action to be taken in the event of an overdose.
Contraindications Hypersensitivity to daptomycin.
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Warnings For additional cautionary notes to warn of the potential risk of using the medicine... click to view Cubicin detailed prescribing infomation
Special Precautions Not indicated for treatment of pneumonia; renal impairment; pregnancy & lactation.
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Adverse Drug Reactions Constipation, nausea, diarrhea, vomiting, inj site reactions, headache, insomnia & rash.
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Drug Interactions Limited experience on use w/ warfarin & HMG-CoA reductase inhibitors.
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Pregnancy Category (US FDA)
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Storage View Cubicin storage conditions for details to ensure optimal shelf-life.
Description View Cubicin description for details of the chemical structure and excipients (inactive components).
Mechanism of Action View Cubicin mechanism of action for pharmacodynamics and pharmacokinetics details.
Presentation/Packing
Form Packing Photo
Cubicin powder for injection Cubicin 500 mg/10 mL x 1's

Manufacturer: AstraZeneca

Distributor: Hong Kong: Zuellig

Macau: Four Star