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Manufacturer Pfizer 
Distributor Hong Kong: Primal/Macau: The Glory Medicina 
Contents Methylprednisolone Na succinate
Indications Endocrine, rheumatic & haematologic disorders. Collagen dermatologic, ophth, GI, resp & neoplastic disease. Allergic & oedematous states. Acute exacerbation of multiple sclerosis. TB meningitis w/ subarachnoid block. Trichinosis w/ neurologic or myocardial involvement. Shock, acute allergic disorders.
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Dosage Life-threatening conditions 30 mg/kg IV over at least 30 min, repeat every 4-6 hr for up to 48 hr. Pulse therapy in RA 1 g/day for 1-4 days or 1 g mthly for 6 mth. Prevention of nausea & vomiting in chemotherapy 250 mg 1 hr before &, pre- & post-chemotherapy. Acute spinal cord injury IV bolus 30 mg/kg over 15 min then pause for 45 min followed by continuous infusion of 5.4 mg/kg/hr for 23 hr. ECG monitoring & defibrillator machine stand-by needed. Other conditions 10-500 mg, doses >250 mg should be given over at least 30 min, subsequent doses, IV or IM, titrated according to conditions & response. Childn & infant Min dose: 0.5 mg/kg every 24 hr. Subsequent doses, IV or IM, titrated according to conditions & response.
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Overdosage View Solu-Medrol overdosage for action to be taken in the event of an overdose.
Contraindications Systemic fungal infection.
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Special Precautions Ocular herpes simplex; psychic derangements; nonspecific ulcerative colitis; active or latent peptic ulcer, renal insufficiency, HTN, osteoporosis, myasthenia gravis; immunisation (defer); active or latent TB; unusual stress; pregnancy, lactation. May mask signs of infection & new infection may appear. Posterior subcapsular cataracts & glaucoma w/ possible damage to optic nerves may occur. Reduce dose gradually.
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Adverse Drug Reactions GI upsets, aseptic necrosis of femoral & humeral heads; peptic ulceration w/ possible perforation & hemorrhage; manifestations of latent DM; anaphylactic reactions w/ or w/o circulatory collapse, cardiac arrest or arrhythmias, bronchospasm. Fluid & electrolyte disturbances.
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Drug Interactions [Click for Solu-Medrol detailed prescribing infomation]
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Pregnancy Category (US FDA)      
     
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. 
Storage View Solu-Medrol storage conditions for details to ensure optimal shelf-life.
Description View Solu-Medrol description for details of the chemical structure and excipients (inactive components).
Mechanism of Action View Solu-Medrol mechanism of action for pharmacodynamics and pharmacokinetics details.
ATC Classification H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations. 

Presentation/Packing
Form Packing Photo
Solu-Medrol powder for injection  Solu-Medrol 500 mg x 1's

Manufacturer: Pfizer
 
Distributor: Hong Kong: Primal
Macau: The Glory Medicina