|
See related Lariam tab information |
|
|
|
Manufacturer |
Roche |
|
Distributor |
Hong Kong: DKSH/Macau: Firma Chun Cheong |
|
Contents |
Mefloquine |
|
Indications |
Therapy & prophylaxis of malaria, particularly caused by strains of P. falciparum resistant to 4-aminoquinolines. |
|
Dosage |
Therapy Childn <45 kg 25 mg/kg body wt. Non-immune patient 45-60 kg Initially 3 tab then 2 tab 6-8 hr later, >60 kg Take an additional tab after a further 6-8 hr. Semi-immune patients: 45-60 kg 3 tab as a single dose, >60 kg Take an additional tab 6-8 hr later. Prophylaxis Adult & childn >45 kg 1 tab wkly starting 2-3 wk before departure, continuous intake during travel period & additional 4 wk after leaving the endemic area. Childn 31-45 kg ¾ tab wkly, 20-30 kg ½ tab wkly, 10-19 kg ¼ tab wkly; 5-9 kg 1/8 tab wkly. |
|
Administration |
Should be taken with food (Best taken w/ meals & a full glass of water.). |
|
Contraindications |
History of psychiatric disturbances or convulsions, young childn, lactation. Hypersensitivity. |
|
Special Precautions |
Renal or hepatic impairment. Cardiac conduction diseases. Pregnancy. Epilepsy. May impair the ability to drive or operate machinery. |
|
Adverse Drug Reactions |
Dizziness, balance disturbance, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite.
View ADR Monitoring Form |
|
Drug Interactions |
Quinine or related compd, valproic acid. Cardioactive agents eg β-blockers. Oral live typhoid vaccines.
View more drug interactions with Lariam |
|
Pregnancy Category (US FDA) |
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. |
|
ATC Classification |
P01BC02 - mefloquine ; Belongs to the class of methanolquinoline antimalarials. |
|
Presentation/Packing |
|
Form |
Packing |
Photo |
|
Lariam tablet |
|
|
|
Manufacturer: |
Roche |
|
Distributor: |
Hong Kong: DKSH
Macau: Firma Chun Cheong
|
|
|
|
