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See related Daxas film-coated tab information |
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Manufacturer |
Nycomed |
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Distributor |
Hong Kong: Zuellig/Macau: The Glory Medicina |
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Contents |
Roflumilast |
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Indications |
Maintenance treatment of severe COPD associated w/ chronic bronchitis in adult patients w/ a history of frequent exacerbations as add on treatment to bronchodilator treatment.
Click to view Daxas detailed prescribing infomation |
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Dosage |
1 tab once daily.
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Overdosage |
View Daxas overdosage for action to be taken in the event of an overdose. |
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Administration |
May be taken with or without food |
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Contraindications |
Moderate or severe hepatic impairment (Child-Pugh B or C).
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Special Precautions |
Decreased body wt. Monitor body wt regularly. Patients w/ severe immunological diseases, severe acute infectious diseases, cancers (except basal cell carcinoma), or patients in immunosuppressants, CHF (NYHA grades III & IV). History or existing psychiatric symptoms eg mood changes or suicidal ideation. Persistent intolerability; concomitant treatment w/ theophylline. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Pregnancy (including women of childbearing potential) & lactation.
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Adverse Drug Reactions |
Decreased wt & appetite, insomnia, headache, diarrhoea, nausea, abdominal pain.
View ADR Monitoring Form |
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Drug Interactions |
Erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine; rifampicin, phenobarb, carbamazepine, phenytoin, theophylline, OC.
View more drug interactions with Daxas |
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Storage |
View Daxas storage conditions for details to ensure optimal shelf-life. |
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Description |
View Daxas description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Daxas mechanism of action for pharmacodynamics and pharmacokinetics details. |
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