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See related Glucophage film-coated tab information |
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Manufacturer |
Merck Serono |
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Distributor |
Hong Kong: Zuellig/Macau: Agencia Lei Va Hong |
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Contents |
Metformin HCl |
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Indications |
Treatment of type 2 DM in adults, as 1st-line therapy irrespective of wt consideration, when dietary management & exercise alone does not result in adequate glycaemic control. Monotherapy or in combination w/ other oral antidiabetic agents, or w/ insulin.
Click to view Glucophage detailed prescribing infomation |
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Dosage |
Adult Initially 500 mg bd-tds, 850 mg bd-tds. Max: 3 g/day. Childn from 10 yr & adolescent Initially 500 mg daily, 850 mg daily. Max: 2 g/day. Should be given alone or w/ insulin.
Click to view Glucophage detailed prescribing infomation |
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Administration |
Should be taken with food (Swallow whole, do not chew/crush.). |
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Contraindications |
Diabetic ketoacidosis, diabetic pre-coma. Renal failure or renal dysfunction, dehydration, severe infection, shock, intravascular administration of iodinated contrast agents. Cardiac or resp failure, recent MI, hepatic insufficiency, acute alcohol intoxication, alcoholism. Lactation.
Click to view Glucophage detailed prescribing infomation |
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Special Precautions |
Lactic acidosis is rare & may occur in significant renal failure. Regular renal monitoring is needed. Suspend therapy during surgery & clinical investigations using IV iodinated contrast media.
Click to view Glucophage detailed prescribing infomation |
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Adverse Drug Reactions |
GI disturbances, metallic taste. Rarely, lactic acidosis, mild erythema.
View ADR Monitoring Form |
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Side Effects |
View Glucophage side effects |
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Drug Interactions |
Alcohol, iodinated contrast agents, glucocorticoids, β2-agonists, diuretics, ACE inhibitors.
View more drug interactions with Glucophage |
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Pregnancy Category (US FDA) |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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Storage |
View Glucophage storage conditions for details to ensure optimal shelf-life. |
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Description |
View Glucophage description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Glucophage mechanism of action for pharmacodynamics and pharmacokinetics details. |
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ATC Classification |
A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes. |
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Presentation/Packing |
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Form |
Packing |
Photo |
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Glucophage film-coated tablet |
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Glucophage 1 g x 60's |
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Glucophage 500 mg x 500's |
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Glucophage 850 mg x 300's |
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Manufacturer: |
Merck Serono |
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Distributor: |
Hong Kong: Zuellig
Macau: Agencia Lei Va Hong |
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