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See related Flagyl information |
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Manufacturer |
sanofi-aventis |
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Distributor |
Hong Kong: LF Asia/Macau: Four Star |
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Contents |
Metronidazole |
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Indications |
Prevention of post-op infections due to anaerobic bacteria particularly Bacteroides sp & anaerobic Strep. Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess & cellulitis, & post-op wound infections. Urogenital trichomoniasis in the female (trichomonal vaginitis) & in male. Bacterial vaginosis, amoebiasis, giardiasis, acute ulcerative gingivitis, leg ulcers & pressure sores. Dental infections (eg acute pericoronitis & acute apical infections). |
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Dosage |
Prophylaxis Adult 400 mg 8 hrly. Childn & infant 7.5 mg/kg 8 hrly. Treatment Adult Initially 800 mg followed by 400 mg 8 hrly. Childn & infant 7.5 mg/kg 8 hrly. |
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Administration |
susp:Should be taken on an empty stomach (Take at least 1 hr before meals.); tab:Should be taken with food (Swallow whole, do not chew/crush.). |
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Special Precautions |
If administered for >10 days, regular clinical & laboratory monitoring are recommended. Re-administer immediately after haemodialysis. Patient w/ hepatic encephalopathy. May affect ability to drive or operate machinery. Pregnancy & lactation. |
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Adverse Drug Reactions |
Peripheral neuropathy or transient epileptiform seizures (intensive or prolonged therapy). Occasionally, taste disorders, oral mucositis, furred tongue, nausea, vomiting, GI disturbances, anorexia, urticaria & angioedema.
View ADR Monitoring Form |
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Drug Interactions |
Alcohol may cause disulfiram-like reaction. Potentiates anticoagulant effect of warfarin-type oral anticoagulants. Plasma levels of lithium may be increased. Phenobarb increases the metabolism of metronidazole. Busulfan.
View more drug interactions with Flagyl |
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Pregnancy Category (US FDA) |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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ATC Classification |
P01AB01 - metronidazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases. |
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Presentation/Packing |
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Form |
Packing |
Photo |
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Flagyl tablet |
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Flagyl 200 mg x 250's |
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Flagyl 400 mg x 100's |
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Flagyl -S oral suspension |
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Flagyl -S 200 mg/5 mL x 100 mL |
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Manufacturer: |
sanofi-aventis |
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Distributor: |
Hong Kong: LF Asia
Macau: Four Star |
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