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Kabiven

2014-09-03 00:36:55 来源: 作者: 【大中小】浏览:545次评论:0条

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Manufacturer	Fresenius Kabi
Distributor	Hong Kong: Zuellig
Contents	Per L Kabiven Purified soya bean oil 39 g, glucose (anhydrous) 97 g, alanine 4.7 g, arginine 3.3 g, aspartic acid 1 g, phenylalanine 2.3 g, glutamic acid 1.6 g, glycine 2.3 g, histidine 2 g, isoleucine 1.6 g, leucine 2.3 g, lysine 2.65 g, methionine 1.6 g, proline 2 g, serine 1.3 g, threonine 1.6 g, tryptophan 0.55 g, tyrosine 0.07 g, valine 2.1 g, Na glycerophosphate (anhydrous) 1.5 g, CaCl₂ 0.22 g, KCl 1.75 g, Mg sulphate 0.47 g, Na acetate 1.4 g. Per L Kabiven Peripheral Purified soya bean oil 35 g, glucose (anhydrous) 68 g, alanine 3.3 g, arginine 2.33 g, aspartic acid 0.71 g, phenylalanine 1.67 g, glutamic acid 1.2 g, glycine 1.67 g, histidine 1.4 g, isoleucine 1.2 g, leucine 1.67 g, lysine 1.9 g, methionine 1.2 g, proline 1.4 g, serine 0.92 g, threonine 1.2 g, tryptophan 0.4 g, tyrosine 0.05 g, valine 1.5 g, Na glycerophosphate (anhydrous) 1 g, CaCl₂ 0.15 g, KCl 1.25 g, Mg sulphate 0.33 g, Na acetate 1 g
Indications	Parenteral nutrition for patients & childn >2 yr when oral or enteral nutrition is impossible, insufficient or contraindicated. Click to view Kabiven detailed prescribing infomation
Dosage	Individualised dosage. *Adult & childn >10 yr* Nitrogen requirements in the normal nutritional state or in mild metabolic stress 0.1-0.15 g nitrogen/kg/day. Nitrogen requirements in moderate to high metabolic stress w/ or w/o malnutrition 0.15-0.3 g nitrogen/kg/day. *Childn 2-10 yr* Kabiven Initially 12.5-25 mL/kg, increased by 10-15 mL/kg/day up to max dose of 40 mL/kg/day. Infusion rate should not exceed 2.6 mL/kg/hr. Kabiven Peripheral Initially 14-28 mL/kg, increased by 10-15 mL/kg/day up to max dose of 40 mL/kg/day. Infusion rate should not exceed 3.7 mL/kg/hr. Click to view Kabiven detailed prescribing infomation
Overdosage	View Kabiven overdosage for action to be taken in the event of an overdose.
Contraindications	Hypersensitivity to egg- or soy protein. Severe hyperlipaemia, severe hepatic insufficiency, severe coagulopathy, inborn errors of amino acid metabolism, severe renal insufficiency w/o access to haemofiltration or dialysis, acute shock, hyperglycemia requiring insulin 6 units/hr, pathologically elevated serum electrolyte levels, acute pulmonary oedema, hyperhydration, decompensated cardiac insufficiency & hypotonic dehydration, hemophagocytotic syndrome. Unstable conditions eg severe posttraumatic conditions, uncompensated diabetes, acute MI, metabolic acidosis, severe sepsis, hyperosmolar coma. Childn & infant <2 yr. Click to view Kabiven detailed prescribing infomation
Special Precautions	Monitor ability to eliminate fat. Correct disturbances of electrolyte & fluid balance before starting infusion. Impaired lipid metabolism eg in renal insufficiency, uncompensated DM, pancreatitis, hepatic impairment, hypothyroidism (w/ hypertriglyceridaemia), sepsis. Regular monitoring of serum glucose, electrolytes, osmolarity, fluid balance, acid-base status & liver enzyme tests. Monitor blood cell count & coagulation when fat is given for a longer period. Phosphate & K intake should be controlled in patients w/ renal insufficiency. Metabolic & lactic acidosis, insufficient cellular O₂ supply, increased serum osmolarity, predisposition to electrolyte retention, malnourished patients & those w/ hyperglycaemia. Do not give w/ blood products. Click to view Kabiven detailed prescribing infomation
Adverse Drug Reactions	Hyperthermia, shivering, chills, nausea, vomiting, transient increase in liver enzymes, thrombophlebitis. View ADR Monitoring Form
Drug Interactions	[Click for Kabiven detailed prescribing infomation] View more drug interactions with Kabiven
Caution For Usage	For caution against possible variation of physical aspect of medicine... click to view Kabiven detailed prescribing infomation
Storage	View Kabiven storage conditions for details to ensure optimal shelf-life.
Description	View Kabiven description for details of the chemical structure and excipients (inactive components).
Mechanism of Action	View Kabiven mechanism of action for pharmacodynamics and pharmacokinetics details.
ATC Classification	B05BA01 - amino acids ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.