|
See related Dynastat powd for inj information |
|
|
|
Manufacturer |
Pfizer |
|
Distributor |
Hong Kong: Zuellig/Macau: The Glory Medicina |
|
Contents |
Parecoxib Na |
|
Indications |
Short-term treatment of post-op pain.
Click to view Dynastat detailed prescribing infomation |
|
Dosage |
IM/IV Initially 40 mg followed by 20-40 mg 6-12 hr later as required. Max: 80 mg/day.
Click to view Dynastat detailed prescribing infomation |
|
Overdosage |
View Dynastat overdosage for action to be taken in the event of an overdose. |
|
Contraindications |
History of serious allergic drug reaction or hypersensitivity to sulphonamides. Patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 inhibitors. Active peptic ulceration or GI bleeding. Severe hepatic dysfunction, inflammatory bowel disease, CHF (NYHA II-IV); treatment of post-op pain following CABG surgery, ischemic heart, peripheral arterial &/or cerebrovascular disease. Pregnancy (3rd trimester) & lactation.
Click to view Dynastat detailed prescribing infomation |
|
Special Precautions |
Patient w/ CV event risk factors eg HTN, hyperlipidemia, DM & smoking. Upper GI complications (perforation, ulcer or bleeding) or patients taking other NSAID or acetylsalicylic acid concomitantly w/ a history of GI disease. Monitor any serious skin reactions (discontinue). Hepatic or renal impairment, compromised cardiac function, preexisting oedema or conditions predisposing to fluid retention. HTN. Dehydration. May mask fever & other signs of inflammation. May impair ability to drive or operate machinery. Elderly.
Click to view Dynastat detailed prescribing infomation |
|
Adverse Drug Reactions |
Nausea; pharyngitis, alveolar osteitis, post-op anaemia, hypokalaemia, agitation, insomnia, hypoaesthesia, dizziness, MI, bradycardia, HTN, hypotension, resp insufficiency, GI disorders, pruritus, hyperhidrosis, back pain, oliguria, peripheral oedema, increased blood creatinine.
View ADR Monitoring Form |
|
Drug Interactions |
Warfarin, diuretics, antihypertensives, ACE inhibitors, cyclosporin, tacrolimus, opioids, fluconazole, rifampicin, phenytoin, carbamazepine, dexamethasone, dextromethorphan, flecainide, propafenone, metoprolol, omeprazole, diazepam, imipramine, methotrexate, lithium.
View more drug interactions with Dynastat |
|
Caution For Usage |
For caution against possible variation of physical aspect of medicine... click to view Dynastat detailed prescribing infomation |
|
Storage |
View Dynastat storage conditions for details to ensure optimal shelf-life. |
|
Description |
View Dynastat description for details of the chemical structure and excipients (inactive components). |
|
Mechanism of Action |
View Dynastat mechanism of action for pharmacodynamics and pharmacokinetics details. |
|
ATC Classification |
M01AH04 - parecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs. |
|
Presentation/Packing |
|
Form |
Packing |
Photo |
|
Dynastat powder for injection |
|
Dynastat 40 mg x 5's |
|
Dynastat (x 5's + solvent (2-mL amp)) 40 mg x 5's |
|
|
|
Manufacturer: |
Pfizer |
|
Distributor: |
Hong Kong: Zuellig
Macau: The Glory Medicina
|
|
|
|
