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Micardis Plus
2014-07-26 14:33:53 来源: 作者: 【 】 浏览:1197次 评论:0
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Manufacturer Boehringer Ingelheim
Distributor Hong Kong: Zuellig/Macau: Agencia Lei Va Hong
Contents Per 40/12.5 mg tab Telmisartan 40 mg, hydrochlorothiazide 12.5 mg. Per 80/12.5 mg tab Telmisartan 80 mg, hydrochlorothiazide 12.5 mg. Per 80/25 mg tab Telmisartan 80 mg, hydrochlorothiazide 25 mg
Indications Treatment of essential HTN in patients whose BP is not adequately controlled on telmisartan alone.
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Dosage Adult 1 tab once daily w/ liqd. Mild to moderate hepatic impairment Max: 1 40/12.5 mg tab daily.
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Overdosage View Micardis Plus overdosage for action to be taken in the event of an overdose.
Administration May be taken with or without food
Contraindications Hypersensitivity to other sulphonamide-derived drugs. Pregnancy (2nd & 3rd trimesters) & lactation. Cholestasis & biliary obstructive disorders. Severe hepatic & renal (CrCl <30 mL/min) impairment. Refractory hypokalaemia, hypercalcaemia.
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Special Precautions Impaired hepatic function or progressive liver disease. Bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney. Mild to moderate renal impairment & kidney transplantation. Vol &/or Na depletion. Severe CHF or underlying renal disease including renal artery stenosis. Primary aldosteronism. Aortic or mitral valve stenosis, obstructive hypertrophic cardiomyopathy. Hypokalaemia, hyperkalaemia, hyponatraemia & hypochloraemic alkalosis, hypercalcaemia, hypomagnesaemia. Diabetes. Hereditary fructose &/or galactose intolerance.
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Adverse Drug Reactions Dizziness; hypokalaemia, anxiety, syncope, paraesthesia, vertigo, tachycardia, arrhythmia, hypotension, orthostatic hypotension, dyspnoea, diarrhoea, dry mouth, flatulence, back pain, muscle spasms, myalgia, erectile dysfunction, chest pain, increased blood uric acid.
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Drug Interactions Lithium, digitalis glycosides, other antihypertensive agents, alcohol, barbiturates, narcotics or antidepressants, baclofen, amifostine, oral antidiabetic agents & insulin, metformin, cholestyramine & colestipol resins, NSAIDs, pressor amines, nondepolarizing skeletal muscle relaxants, probenecid, sulfinpyrazone & allopurinol, Ca salts, β-blockers & diazoxide, anticholinergic agents, amantadine, cytotoxic agents. Drugs associated w/ K loss & hypokalaemia. Drugs that may increase K levels or induce hyperkalaemia. Drugs affected by serum K disturbances.
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Pregnancy Category (US FDA)
 
         
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
 
 
         
in 2nd & 3rd trimesters.
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Storage View Micardis Plus storage conditions for details to ensure optimal shelf-life.
Description View Micardis Plus description for details of the chemical structure and excipients (inactive components).
Mechanism of Action View Micardis Plus mechanism of action for pharmacodynamics and pharmacokinetics details.

Presentation/Packing
Form Packing Photo
Micardis Plus 40/12.5 mg tablet
Micardis Plus 30's Micardis Plus 40_12.5 mg tab_25244.gif White Pink Oval
Micardis Plus 80/12.5 mg tablet
Micardis Plus 30's Micardis Plus 80_12.5 mg tab_26542.gif White Pink Oval
Micardis Plus 80/25 mg tablet
Micardis Plus 30's

 

Manufacturer: Boehringer Ingelheim
Distributor: Hong Kong: Zuellig
Macau: Agencia Lei Va Hong
 
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