Generic Name and Formulations:
Dihydrocodeine bitartrate 16mg, aspirin 356.4mg, caffeine 30mg; caps.

Company:
Caraco Pharmaceutical Laboratories, LTD.
Indications for SYNALGOS-DC:
Moderate to moderately severe pain.

Adult Dose for SYNALGOS-DC:
2 caps every 4hrs as needed.

Children's Dose for SYNALGOS-DC:
Not recommended.

Pharmacological Class:
Opioid + salicylate.

Contraindications:
NSAID allergy. Post-op pain management in children who have undergone tonsillectomy and/or adenoidectomy.

Warnings/Precautions:
Risk of respiratory depression and death related to ultra-rapid metabolizers of codeine (esp. children in post-op tonsillectomy and/or adenoidectomy). Peptic ulcer. Coagulation abnormalities. Obstructive sleep apnea. Asthma. Head injury. Increased intracranial pressure. Acute abdomen. Impaired renal, hepatic, thyroid, or adrenocortical function. GI or GU obstruction. Use lowest effective dose for shortest duration. Drug abusers. Elderly. Debilitated. Pregnancy. Nursing mothers.

Interactions:
Potentiation with alcohol, CNS depressants, anticoagulants, hypoglycemics, plasma protein bound drugs, MAOIs, tricyclic antidepressants, anticholinergics. Alcohol, NSAIDs, corticosteroids increase risk of GI bleeding. May antagonize uricosurics.

Adverse Reactions:
Lightheadedness, dizziness, sedation, allergic reactions, nausea, vomiting, gastric upset, constipation, urinary retention, prolonged bleeding time, respiratory depression.

How Supplied:
Caps—100