Linzess (Linaclotide Capsules)
LINZESS Rx
Constipation and bowel cleansers  Only 4 drugs may be compared at once
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Generic Name and Formulations:
Linaclotide 72mcg, 145mcg, 290mcg; caps.
Company:
Allergan
 
Select therapeutic use: Colorectal disorders
Constipation and bowel cleansers
Indications for LINZESS:
Irritable bowel syndrome with constipation (IBS-C).

Adult:
Swallow whole. Take on empty stomach, at least 30 mins before first meal of the day. May open caps and mix contents in applesauce or with water if unable to swallow; or, may give with water via NG or gastrostomy tube. 290mcg once daily.

Children:
<6yrs: contraindicated. 6–<18yrs: avoid.

Contraindications:
Children <6yrs old. Known or suspected mechanical GI obstruction.

Warnings/Precautions:
Consider dose suspension and rehydration if severe diarrhea occurs. Pregnancy. Nursing mothers.

Pharmacological Class:
Guanylate cyclase-C agonist.

Adverse Reactions:
Diarrhea, abdominal pain, flatulence, abdominal distention.

Metabolism:
GI.

Elimination:
Fecal.

Generic Availability:
NO

How Supplied:
Caps—30