Norvasc(Amlodipine Besylate)
Description
Norvasc controls high blood pressure for a full 24 hours and can be used to treat the chest pain of angina. NORVASC works to relax your cat's blood vessels, allowing blood to flow more easily through them. The end result is lower blood pressure and less angina which makes for a healthier kitty.
NORVASC Rx
Generic Name and Formulations:
Amlodipine (as besylate) 2.5mg, 5mg, 10mg; tabs.
Company:
Pfizer Inc.
Select therapeutic use: Angina
Hypertension
Indications for NORVASC:
Vasospastic and chronic stable angina.
Adult:
10mg once daily. Elderly or hepatic impairment: 5mg once daily.
Children:
Not recommended.
Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy (Cat.C). Nursing mothers: not recommended.
Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant sildenafil; monitor for hypotension. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.
Pharmacological Class:
Calcium channel blocker (CCB) (dihydropyridine).
Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, drowsiness.
How Supplied:
Tabs 2.5mg, 10mg—90; 5mg—90, 300
Indications for NORVASC:
Hypertension.
Adult:
5mg daily. Adjust at 7–14 day intervals; usual max 10mg daily. Small, fragile, elderly, hepatic impaired, patients on other antihypertensives: 2.5mg daily.

Children:
<6yrs: not established. 6–17yrs: 2.5–5mg daily.

Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant sildenafil; monitor for hypotension. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.

Pharmacological Class:
Calcium channel blocker (CCB) (dihydropyridine).

Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, drowsiness.

How Supplied:
Tabs 2.5mg, 10mg—90; 5mg—90, 300
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NORVASC TAB 5MG UD 100  AMLODIPINE BESYLATE     00069-1530-41
NORVASC TAB 5MG 90  AMLODIPINE BESYLATE     00069-1530-68
NORVASC TAB 2.5MG 90  AMLODIPINE BESYLATE     00069-1520-68
NORVASC TAB 10MG 90  AMLODIPINE BESYLATE     00069-1540-68