Generic Name and Formulations:
Lidocaine 7%, tetracaine 7%; emulsion cream.
Company:
Galderma Laboratories, Inc.
Topical pain relief
Topical pain relief
 
Indications for PLIAGLIS:
Local analgesia for superficial dermatological procedures (eg, dermal filler injection, pulsed dye laser therapy, facial laser resurfacing, laser-assisted tattoo removal).

Adult:
Do not exceed recommended dose or duration. Apply to intact skin prior to procedure; spread evenly and thinly across treatment area using a metal spatula or tongue depressor. Dermal filler inj or facial laser ablation: apply for 20–30 mins. Laser-assisted tattoo removal: apply for 60 mins. Amount (length) to apply: see full labeling.

Children:
Not established.

Contraindications:
PABA hypersensitivity.

Warnings/Precautions:
Risk of methemoglobinemia. Severe hepatic impairment. Pseudocholinesterase deficiency. Avoid contact with eyes, mucous membranes, or areas with a compromised skin barrier (eg, broken or inflamed). Do not ingest; may be toxic to children and pets. Acutely ill. Debilitated. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:
Toxicity may be potentiated by Class I antiarrhythmics (eg, tocainide, mexiletine); caution. Additive effects with other local anesthetics; consider the amount absorbed from all formulations.

Pharmacological Class:
Topical anesthetic (amide-type + ester-type).

Adverse Reactions:
Localized reactions (eg, erythema, skin discoloration, edema), allergic reactions (eg, urticaria, angioedema, bronchospasm, shock).

Metabolism:
Lidocaine: hepatic.

Elimination:
Lidocaine: renal.

Generic Availability:
NO

How Supplied:
Cream—30g, 100g