Generic Name and Formulations:
Cephalexin 250mg, 500mg, 750mg; caps.
Company:
Shionogi, Inc.
Select therapeutic use: Bacterial infections
Indications for KEFLEX:
Susceptible infections including otitis media, skin and skin structure, bone, respiratory or genitourinary tract.
Adult:
1–4g/day in divided doses. Usual dose: 250mg every 6hrs. Strep pharyngitis, skin and skin structure, and uncomplicated cystitis (>15yrs of age): 500mg every 12hrs. Treat cystitis for 7–14 days. Max 4g/day.
Children:
25–50mg/kg per day in divided doses; max 100mg/kg per day. Otitis media: 75–100mg/kg per day in 4 divided doses. Strep pharyngitis (>1yr of age) or skin and skin structure: may give in 2 divided doses every 12hrs.
Warnings/Precautions:
Penicillin or other allergy. Severe renal dysfunction. GI disease (esp. colitis). Discontinue if colitis occurs and treat. Pregnancy (Cat.B). Nursing mothers.
Interactions:
Potentiates metformin (monitor and adjust metformin dose). Potentiated by probenecid. May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln.
Pharmacological Class:
Cephalosporin.
Adverse Reactions:
Diarrhea, other GI disturbances, dizziness, fatigue, headache, hypersensitivity reactions, itch; rare: blood dyscrasias, elevated liver enzymes.
How Supplied:
Caps 250mg, 500mg—20, 100; 750mg—50