ISORDIL TITRADOSE（selegiline）
ISORDIL TITRADOSE
Generic Name and Formulations:
Isosorbide dinitrate 5mg, 40mg; scored oral tabs.
Company:
Valeant Pharmaceuticals, Inc

Select therapeutic use: Angina
Indications for ISORDIL TITRADOSE:
Prophylaxis of angina. Not for acute attacks.

Adult:
Initially 5–20mg 2–3 times per day. Maintenance: 10–40mg 2–3 times per day; allow a daily dose-free interval of at least 14hrs.

Children:
Not established.

Contraindications:
Concomitant PDEIs (eg, sildenafil, tadalafil, vardenafil), riociguat.

Warnings/Precautions:
Recent MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Tolerance may develop. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:
See Contraindications. Severe hypotension with sildenafil. Hypotension potentiated with alcohol, other vasodilators, calcium channel blockers.

See Also:
Isosorbide dinitrate

Pharmacological Class:
Nitrate.

Adverse Reactions:
Headache, orthostatic hypotension, paradoxical bradycardia.

Note:
Sublingual tabs formerly known under the brand names Isordil, Sorbitrate.

Generic Availability:
Titradose (YES)

How Supplied:
Sublingual—contact supplier; Titradose—100