Generic Name and Formulations:
Ipratropium bromide 20mcg, albuterol 100mcg (equivalent to 120mcg albuterol sulfate); per actuation; inhalation spray; CFC-free.
Company:
Boehringer Ingelheim Pharmaceuticals

Select therapeutic use: Asthma/COPD
Indications for COMBIVENT RESPIMAT:
COPD when a second aerosol bronchodilator is needed.

Adult:
1 inh 4 times daily; max 6 inh/day.

Children:
Not established.

Contraindications:
Atropine allergy.

Warnings/Precautions:
Avoid excessive use. Discontinue if paradoxical bronchospasm occurs. Cardiovascular disorders. Arrhythmias. Hypertension. Diabetes. Hyperthyroidism. Seizure disorders. Sensitivity to sympthomimetic amines. Narrow angle glaucoma. GI or GU obstruction. Hepatic or renal disease. Pregnancy (Cat. C). Labor & delivery. Nursing mothers: not recommended.

Interactions:
Extreme caution within 2 weeks of MAOIs or tricyclic antidepressants (increased cardiovascular effects). Caution with other anticholinergics, sympathomimetics, drugs that lower serum potassium. Antagonized by beta-blockers.

Pharmacological Class:
Anticholinergic + beta-2 agonist.

Adverse Reactions:
Upper respiratory infection, nasopharyngitis, cough, bronchitis, headache, dyspnea; paradoxical bronchospasm, urinary retention, hypokalemia, hypersensitivity reactions, ocular effects.

Elimination:
Ipratropium bromide: renal.

Generic Availability:
NO

How Supplied:
Inhaler—4g (120 inh)