Generic Name for NEXICLON XR ORAL SUSPENSION
Clonidine 0.09mg/mL; ext-rel oral susp.
Legal Classification
Rx
Pharmacological Classification
Central α-agonist.
Manufacturer
NextWave
INDICATIONS FOR NEXICLON XR ORAL SUSPENSION
Hypertension.
ADULT DOSE FOR NEXICLON XR ORAL SUSPENSION
Initially 0.17mg daily at bedtime; may increase by increments of 0.09mg once daily at weekly intervals. End-stage kidney disease on maintenance dialysis: initially 0.09mg/day; titrate slowly. Usual range 0.17mg–0.52mg once daily. Elderly: may need lower initial dose. Switching from immediate-release clonidine tablets: see literature.
CHILDREN'S DOSING FOR NEXICLON XR ORAL SUSPENSION
Not recommended.
WARNINGS/PRECAUTIONS FOR NEXICLON XR ORAL SUSPENSION
Severe coronary insufficiency. Conduction disturbances. Recent MI. Cerebrovascular disease. Renal failure. Avoid abrupt cessation, reduce dose gradually over 2–4 days; concomitant β-blocker, withdraw β-blocker several days before gradual discontinuation of clonidine. If local reaction occurs from patch, using tabs may cause generalized rash. Discontinue 28hrs before surgery; resume the following day. Elderly. Pregnancy (Cat.C). Nursing mothers.
INTERACTIONS FOR NEXICLON XR ORAL SUSPENSION
Alcohol may increase rate of release. Antagonized by tricyclic antidepressants. Potentiates CNS depressants. Possible additive effects with drugs known to affect sinus node function or AV nodal conduction (eg, digitalis, calcium channel blockers, β-blockers).

ADVERSE REACTIONS NEXICLON XR ORAL SUSPENSION
Dry mouth, drowsiness, dizziness.

HOW IS NEXICLON XR ORAL SUSPENSION SUPPLIED
Tabs—90
Susp—118mL