Generic Name and Formulations:
Tiotropium (as bromide monohydrate) 2.5mcg; per actuation; inh spray; contains benzalkonium chloride.

Company:
Boehringer Ingelheim Pharmaceuticals
Indications for SPIRIVA RESPIMAT:
Long-term maintenance treatment of bronchospasm due to COPD, including chronic bronchitis and emphysema. To reduce exacerbations of COPD.

Adult:
2 inh (5mcg) once daily.

Children:
Not established.

Contraindications:
Allergy to atropine or its derivatives (eg, ipratropium).

Warnings/Precautions:
Not for the relief of acute symptoms. Discontinue if immediate hypersensitivity reactions (eg, angioedema) or paradoxical bronchospasm occurs; consider alternative therapy. Monitor for signs/symptoms of worsening narrow-angle glaucoma; or worsening GI or GU obstruction. Moderate-to-severe renal impairment; monitor for anticholinergic effects. HandiHaler: avoid getting powder into eyes; or allergy to milk proteins. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.

Interactions:
Avoid other anticholinergics.

See Also:
SPIRIVA HANDIHALER

Pharmacological Class:
Long-acting anticholinergic.

Adverse Reactions:
Upper respiratory tract infection, dry mouth, sinusitis, pharyngitis, non-specific chest pain, urinary tract infection, dyspepsia, rhinitis, other anticholinergic effects (eg, urinary retention/difficulty, constipation, increased heart rate, blurred vision, glaucoma), GI upset, epistaxis, rash, arthritis, cough, flu-like symptoms, paradoxical bronchospasm, angioedema.

Generic Availability:
NO

How Supplied:
HandiHaler (caps w. inh device)—5, 30, 90; Respimat (cartridge w. inh device)—4g (28, 60 inh)