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Evekeo(amphetamine sulfate tablets, USP)(一)
2016-01-21 06:30:17 来源: 作者: 【 】 浏览:1413次 评论:0

EVEKEO: Another Approach to Treating ADHD
Attention deficit hyperactivity disorder (ADHD) is different for everyone. ADHD treatment is also very individualized. That's why it's good to know about available treatments, including EVEKEO.

EVEKEO is made up of 2 molecules. It is the only ADHD medicine that is half dextroamphetamine and half levoamphetamine.
Generic Name and Formulations:
Amphetamine sulfate 5mg, 10mg; tabs.

Company:
Arbor Pharmaceuticals, Inc.
Indications for EVEKEO:
Attention deficit hyperactivity disorder.

Adults and Children:
Individualize. Avoid late evening doses; give first dose upon awakening and additional doses at 4–6hr intervals; <3yrs: not recommended. 3–5yrs: initially 2.5mg daily, may increase by 2.5mg/day at weekly intervals. ≥6yrs: initially 5mg once or twice daily; may increase by 5mg/day at weekly intervals; max 40mg/day.

Contraindications:
Advanced arteriosclerosis. Symptomatic cardiovascular disease. Moderate-to-severe hypertension. Hyperthyroidism. History of drug abuse. Agitation. During or within 14 days of MAOIs. Hypersensitivity to sympathomimetics.

Warnings/Precautions:
High abuse potential. Known structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease: not recommended. Hypertension. Heart failure. Recent MI. Arrhythmias. Assess cardiovascular status. Psychosis. Bipolar disorder. Depression. Monitor for worsening of aggressive behavior or hostility. Seizure disorders; discontinue if occur. eva luate for tics or Tourette's syndrome prior to therapy. Peripheral vasculopathy including Raynaud's phenomenon; monitor for digital changes. Monitor HR, BP, growth in children. Reeva luate periodically. Write ℞ for smallest practical amount. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:
See Contraindications. Avoid concomitant antacids. Potentiated by alkalinizers (eg, sodium bicarbonate, acetazolamide, some thiazides), propoxyphene. Antagonized by acidifiers, chlorpromazine, haloperidol, lithium. May antagonize effects of adrenergic blockers, antihistamines, veratrum alkaloids, antihypertensives. May potentiate effects of tricyclic antidepressants, meperidine, norepinephrine. May delay absorption of phenytoin, phenobarbital, ethosuximide. Monitor effects when concomitant PPIs. Convulsions with propoxyphene overdose and amphetamines. May interfere with urinary steroid tests.

Pharmacological Class:
CNS stimulant.

Adverse Reactions:
Palpitations, tachycardia, BP increase, overstimulation, restlessness, dizziness, insomnia, euphoria, dyskinesia, dysphoria, tremor, headache, motor/phonic tics, Tourette's syndrome, dry mouth, unpleasant taste, diarrhea, constipation, anorexia, weight loss, urticaria, impotence, libido change, prolonged erection, rhabdomyolysis; serious cardiovascular events, visual disturbances.

Generic Availability:
NO

How Supplied:
Tabs—100

Indications for EVEKEO:
Short-term adjunct in managing exogenous obesity.

Adult:
Take 30–60 mins before meals. Usually up to 30mg/day in divided doses of 5–10mg.

Children:
Not recommended.

Contraindications:
Advanced arteriosclerosis. Symptomatic cardiovascular disease. Moderate-

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