Colcrys (Generic Colchicine) 0.6mg
The generic version of Colchicine 0.6mg contains the same active ingredients as the original brand name drug, and is as just as effective. CanadaDrugsOnline.com provides generic Colchicine tablets which meet the quality and safety standards to ensure your health. Generic Colchicine is made by Odan or Jamp Pharma in Canada. Colchicine belongs to a class of medications called anti-gout or anti-inflammatory drugs, and is used to treat:
• Acute attacks of gout (also called gouty arthritis)
• Familial Mediterranean fever (FMF)
• Symptoms of Behcets syndrome such as pain, redness, and swelling
Colchicine Generic Dosage
Colchicine tablets should be taken as directed on the package and by your doctor. Colchicine generic is available in various doses, including 0.5 mg, 0.6 mg, and 1.0 mg. You should store Colchicine in a cool dry place away from direct sunlight. Only use Colchicine as directed by your doctor, and never exceed the stated dose.
COLCRYS Rx
Generic Name and Formulations:
Colchicine 0.6mg; tabs.
Company:
Takeda Pharmaceuticals North America, Inc.
Indications for COLCRYS:
Prophylaxis and treatment of acute gout flares. Familial Mediterranean fever (FMF).
Adult:
Gout prophylaxis: >16yrs: 0.6mg once or twice daily; max 1.2mg/day. Gout treatment: 1.2mg at first sign of gout flare, then 0.6mg 1 hour later; max 1.8mg over a 1 hour period; may be given during prophylaxis at max 1.2mg at first sign of flare, then 0.6mg 1 hour later, wait 12 hours, then resume prophylactic dose. FMF: Usual range: 1.2mg–2.4mg daily; may give in 1–2 divided doses. May increase/decrease dose (depending on tolerability) in increments of 0.3mg/day to max daily dose. For all: concomitant CYP3A4 and/or P-glycoprotein inhibitors, severe renal or hepatic impairment: reduce dose (see literature).
Children:
FMF: <4yrs: not recommended. Give as a single or divided dose twice daily. 4–6yrs: 0.3mg–1.8mg daily; 6–12yrs: 0.9mg–1.8mg daily. May increase/decrease dose (depending on tolerability) in increments of 0.3mg/day to max daily dose. Concomitant CYP3A4 and/or P-glycoprotein inhibitors, severe renal or hepatic impairment: reduce dose (see literature).
Contraindications:
Renal or hepatic impairment with concomitant strong CYP3A4 or P-glycoprotein inhibitors (life-threatening toxicity possible).
Warnings/Precautions:
Monitor for toxicity; if present, consider temporary interruption or discontinuation. Renal or hepatic impairment. Elderly. Pregnancy (Cat.C). Nursing mothers.
Interactions:
See Contraindications. Potentiated by concomitant CYP3A4 inhibitors (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, amprenavir, aprepitant, diltiazem, erythromycin, fluconazole, fosamprenavir, verapamil, grapefruit juice) and/or P-glycoprotein inhibitors (eg, cyclosporine, ranolazine). Concomitant statins, gemfibrozil, fibrates, digoxin may potentiate myopathy and rhabdomyolysis.
Pharmacological Class:
Antiinflammatory (alkaloid).
Adverse Reactions:
GI upset, abdominal pain, pharyngolaryngeal pain; blood dyscrasias (myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, pancytopenia, aplastic anemia), neuromuscular toxicity, rhabdomyolysis, overdosage (may be fatal).
Generic Availability:
YES
How Supplied:
Tabs—30, 60, 100, 250, 500, 1000
http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5ecaa34e-1bed-49a5-b97c-a8f8c0d885a7
