Generic Name and Formulations:
Metronidazole 250mg, 500mg; scored tabs.

Company:
Pfizer Inc.
Indications for FLAGYL:
Susceptible anaerobic infections, including intraabdominal, skin and skin structures, gynecologic, bacterial septicemia, bone and joint, CNS, lower respiratory tract, endocarditis.

Adult:
Parenteral form usually used first. 7.5mg/kg every 6 hours for 7–10 days; max 4g/day.

Children:
Not recommended.

See Also:
FLAGYL 375

FLAGYL I.V. INJECTION

Pharmacological Class:
Nitroimidazole.

Contraindications:
Pregnancy (1st trimester for trichomoniasis).

Warnings/Precautions:
CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. Candidiasis. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:
Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.

Adverse Reactions:
Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.

How Supplied:
Tabs—50, 100; Caps 375mg—50; IV—24