Trental® 400
Oxypentifylline
Consumer Medicine Information (CMI)
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. This page contains answers to some common questions about Trental 400. It does not contain all the information that is known about Trental 400. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risk of you using this medicine against the benefits he/she expects it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Bookmark or print this page, you may need to read it again.

What Trental 400 is used for
Trental 400 is a type of medicine used to improve the circulation of the blood.
Trental 400 is used to treat the symptoms of a condition called chronic occlusive arterial disease. Symptoms of this disease can include lameness and pain, usually in the leg muscles.
Trental 400 is a slow release tablet, which means that the active ingredient is released slowly over several hours.
Your doctor, however, may prescribe Trental 400 for another purpose.
Ask your doctor if you have any questions about why it has been prescribed for you.
This medicine is only available with a doctor's prescription.
Before you take it
When you must not take it
Do not take Trental 400 if you have:
had a recent operation
bleeding problems
heart problems, such as having suffered a heart attack
kidney or liver problems
stomach ulcers or a history of stomach ulcers
had a allergic reaction to caffeine or theophylline (a medicine used to treat asthma)
Do not take Trental 400 if you are allergic to it or any of the ingredients listed at the end of this leaflet.
Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing.
Do not give Trental 400 to a child or adolescent.
There is no experience with its use in children or adolescents under 18 years old.
Do not take it if you are pregnant or intend to become pregnant.
It may affect your developing baby if you take it during pregnancy. Your doctor or pharmacist will discuss the risks and benefits of taking it if you are pregnant.
Do not take it if you are breastfeeding or planning to breastfeed.
Do not take it after the expiry date (EXP) printed on the pack.
If you take it after the expiry date has passed, it may not work as well.
Do not take it if the packaging is damaged or shows signs of tampering.
Before you start to take it
Tell your doctor or pharmacist if you have allergies to:
any of the ingredients listed at the end of this leaflet
any other medicines including caffeine or theophylline (a medicine used to treat asthma)
any other substances, such as foods, preservatives or dyes.
Tell your doctor or pharmacist if you are pregnant or intend to become pregnant.
Like most medicines of this kind, Trental 400 is not recommended to be used during pregnancy. Your doctor or pharmacist will discuss the risks and benefits of taking it if you are pregnant.
Tell your doctor or pharmacist if you are breastfeeding or planning to breastfeed.
Trental 400 passes into breast milk and there is a possibility your baby may be affected. Your doctor will discuss the risks and benefits of taking it if you are breastfeeding or planning to breastfeed.
Tell your doctor if you have or have had any medical conditions