Generic Name and Formulations:
Metronidazole 375mg; caps.
Company:
Pfizer Inc.
Indications for FLAGYL 375:
Susceptible anaerobic infections, including intraabdominal, skin and skin structures, gynecologic, bacterial septicemia, bone and joint, CNS, lower respiratory tract, endocarditis.
Adult Dose for FLAGYL 375:
Parenteral form usually used first. 7.5mg/kg every 6 hours for 7–10 days; max 4g/day.
Children's Dose for FLAGYL 375:
Not recommended.
See Also:
FLAGYL
FLAGYL I.V. INJECTION
Pharmacological Class:
Nitroimidazole.
Contraindications:
Pregnancy (1st trimester for trichomoniasis).
Warnings/Precautions:
CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. Candidiasis. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.
Interactions:
Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.
Adverse Reactions:
Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.
How Supplied:
Tabs—50, 100; Caps 375mg—50; IV—24
Indications for FLAGYL 375:
Amebic dysentery. Amebic liver abscess.
Adult Dose for FLAGYL 375:
Dysentery: 750mg. Abscess: 500–750mg. Both: 3 times daily for 5–10 days.
Children's Dose for FLAGYL 375:
35–50mg/kg/day in 3 divided doses for 10 days.
See Also:
FLAGYL
Pharmacological Class:
Nitroimidazole.
Contraindications:
Pregnancy (1st trimester for trichomoniasis).
Warnings/Precautions:
CNS disease. Discontinue if neurologic symptoms occur. Severe hepatic disease: reduce dose. History of blood dyscrasias. Candidiasis. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.
Interactions:
Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.
Adverse Reactions:
Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.
How Supplied:
Tabs—50, 100; Caps 375mg—50
Indications for FLAGYL 375:
Trichomoniasis.
Adult Dose for FLAGYL 375:
375mg twice daily for 1 wk. Treat consorts also.
Children's Dose for FLAGYL 375:
Not recommended.
See Also:
FLAGYL
FLAGYL ER
Pharmacological Class:
Antiprotozoal/antibacterial.
Contraindications:
Pregnancy (1st trimester for trichomoniasis).
Warnings/Precautions:
CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B, 2nd and 3rd trimesters). Nursing mothers: not recommended.
Interactions:
Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.
Adverse Reactions:
GI upset, headache, metallic taste, dysuria, cystitis, incontinence, Candida overgrowth, seizures, peripheral neuropathy, ECT changes; neutropenia, pancreatitis (rare).
How Supplied:
Tabs—50, 100; ER—30; Caps 375mg—50
