Nesacaine是麻醉剂表示为生产局部或区域麻醉的，特别是用于口腔外科。
Nesacaine（如可卡因），有收缩血管的减少出血，不像其他局部麻醉剂利多卡因一样的优势。
Nesacaine是酯的麻醉剂。它被代谢在血浆中，通过水解酶拟胆碱酯酶到对氨基苯甲酸（PABA），然后将其通过肾脏进入尿液排泄。
Nesacaine1％和2％的注射剂，在多剂量小瓶中与对羟基苯甲酸甲酯防腐剂，是表示用于制作局部麻醉通过渗透和外周神经阻滞。它们不是用于腰椎骶管或硬膜外麻醉。
Nesacaine-MPF2％和3％的注射剂，在单剂量小瓶无防腐剂和无EDTA，指示用于生产局部麻醉通过浸润，外周和中枢的神经阻滞，其中包括腰椎和骶硬膜外块。
Nesacaine和Nesacaine，强积金注射不用于蛛网膜下腔给药。
适应症：局部麻醉
NESACAINE-MPF
Generic Name and Formulations:
Chloroprocaine HCl 20mg/mL, 30mg/mL; soln for inj; preservative-free.

Company:
Fresenius Kabi USA
Indications for NESACAINE-MPF:
Production of local anesthesia by infiltration, peripheral and central nerve block, including lumbar and caudal epidural blocks.

Adult Dose for NESACAINE-MPF:
Epidural anesthesia: administer test dose first; monitor for CNS or cardiovascular toxicity. See literature for dosing based on procedure. Individualize. Max single recommended dose: 11mg/kg, not to exceed max total dose of 800mg. Debilitated, elderly, acutely ill (cardiac and/or liver disease): reduce dose.

Children's Dose for NESACAINE-MPF:
<3yrs: see literature. Individualize based on age and weight. ≥3yrs: max 11mg/kg.

See Also:
NESACAINE

Pharmacological Class:
Local anesthetic.

Warnings/Precautions:
Not for subarachnoid administration. Lumbar and caudal epidural anesthesia: caution with existing neurological disease, spinal deformities, septicemia, severe hypertension. To be administered under the supervision of experienced clinicians. Have intubation, artificial respiration, oxygen therapy and reversal agents available. Hypotension. Heart block. Monitor cardiovascular and respiratory vital signs. Hepatic impairment. Retrobulbar block. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.

Interactions:
Concomitant sulfonamides: not recommended.

Adverse Reactions:
CNS effects (eg, excitation, depression, restlessness, anxiety, dizziness, tremors), cardiovascular effects (eg, myocardium depression, decreased cardiac output, heart block, hypotension, bradycardia, ventricular arrhythmias, cardiac arrest), allergic-type reactions, neurologic effects (eg, spinal block, urinary retention, paresthesia, weakness, headache, paralysis of lower extremities).

How Supplied:
Nesacaine: Multi-dose vial (30mL)—1; Nesacaine-MPF: Single-dose vial (20mL)—1